11q13 is a susceptibility locus for hormone receptor positive breast cancer
Identifieur interne : 005743 ( Main/Exploration ); précédent : 005742; suivant : 00574411q13 is a susceptibility locus for hormone receptor positive breast cancer
Auteurs : Diether Lambrechts [Belgique] ; Therese Truong [France] ; Christina Justenhoven [Allemagne] ; Manjeet K. Humphreys [Royaume-Uni] ; Jean Wang [Royaume-Uni] ; John L. Hopper [Australie] ; Gillian S. Dite [Australie] ; Carmel Apicella [Australie] ; Melissa C. Southey [Australie] ; Marjanka K. Schmidt [Pays-Bas] ; Annegien Broeks [Pays-Bas] ; Sten Cornelissen [Pays-Bas] ; Richard Van Hien [Pays-Bas] ; Elinor Sawyer [Royaume-Uni] ; Ian Tomlinson [Royaume-Uni] ; Michael Kerin [Irlande (pays)] ; Nicola Miller [Irlande (pays)] ; Roger L. Milne [Espagne] ; M. Pilar Zamora [Espagne] ; José Ignacio Arias Pérez [Espagne] ; Javier Benítez [Espagne] ; Ute Hamann [Allemagne] ; Yon-Dschun Ko [Allemagne] ; Thomas Brüning [Allemagne] ; Jenny Chang-Claude [Allemagne] ; Ursel Eilber [Allemagne] ; Rebecca Hein [Allemagne] ; Stefan Nickels [Allemagne] ; Dieter Flesch-Janys [Allemagne] ; Shan Wang-Gohrke [Allemagne] ; Esther M. John [États-Unis] ; Alexander Miron [États-Unis] ; Robert Winqvist [Finlande] ; Katri Pylk S [Finlande] ; Arja Jukkola-Vuorinen [Finlande] ; Mervi Grip [Finlande] ; Georgia Chenevix-Trench [Australie] ; Jonathan Beesley [Australie] ; Xiaoqing Chen [Australie] ; Kconfab Investigators [Australie] ; Florence Menegaux [France] ; Emilie Cordina-Duverger [France] ; Chen-Yang Shen [Taïwan] ; Jyh-Cherng Yu [Taïwan] ; Pei-Ei Wu [Taïwan] ; Ming-Feng Hou [Taïwan] ; Irene L. Andrulis [Canada] ; Teresa Selander [Canada] ; Gord Glendon [Canada] ; Anna Marie Mulligan [Canada] ; Hoda Anton-Culver [États-Unis] ; Argyrios Ziogas [États-Unis] ; Kenneth R. Muir [Royaume-Uni] ; Artitaya Lophatananon [Royaume-Uni] ; Suthee Rattanamongkongul [Thaïlande] ; Puttisak Puttawibul [Thaïlande] ; Michael Jones [Royaume-Uni] ; Nicholas Orr [Royaume-Uni] ; Alan Ashworth [Royaume-Uni] ; Anthony Swerdlow [Royaume-Uni] ; Gianluca Severi [Australie] ; Laura Baglietto [Australie] ; Graham Giles [Australie] ; Melissa Southey [Australie] ; Federik Marmé [Allemagne] ; Andreas Schneeweiss [Allemagne] ; Christof Sohn [Allemagne] ; Barbara Burwinkel [Allemagne] ; Betul T. Yesilyurt [Belgique] ; Patrick Neven [Belgique] ; Robert Paridaens [Belgique] ; Hans Wildiers [Belgique] ; Hermann Brenner [Allemagne] ; Heiko Müller [Allemagne] ; Volker Arndt [Allemagne] ; Christa Stegmaier [Allemagne] ; Alfons Meindl [Allemagne] ; Sarah Schott [Allemagne] ; Claus R. Bartram [Allemagne] ; Rita K. Schmutzler [Allemagne] ; Angela Cox [Royaume-Uni] ; Ian W. Brock [Royaume-Uni] ; Graeme Elliott [Royaume-Uni] ; Simon S. Cross [Royaume-Uni] ; Peter A. Fasching [États-Unis] ; Ruediger Schulz-Wendtland [Allemagne] ; Arif B. Ekici [Allemagne] ; Matthias W. Beckmann [Allemagne] ; Olivia Fletcher [Royaume-Uni] ; Nichola Johnson [Royaume-Uni] ; Isabel Dos Santos Silva [Royaume-Uni] ; Julian Peto [Royaume-Uni] ; Heli Nevanlinna [Finlande] ; Taru A. Muranen [Finlande] ; Kristiina Aittom Ki [Finlande] ; Carl Blomqvist [Finlande] ; Thilo Dörk [Allemagne] ; Peter Schürmann [Allemagne] ; Michael Bremer [Allemagne] ; Peter Hillemanns [Allemagne] ; Natalia V. Bogdanova [Allemagne] ; Natalia N. Antonenkova [Biélorussie] ; Yuri I. Rogov [Biélorussie] ; Johann H. Karstens [Allemagne] ; Elza Khusnutdinova [Russie] ; Marina Bermisheva [Russie] ; Darya Prokofieva [Russie] ; Shamil Gancev [Russie] ; Anna Jakubowska [Pologne] ; Jan Lubinski [Pologne] ; Katarzyna Jaworska [Pologne] ; Katarzyna Durda [Pologne] ; B Rge G. Nordestgaard [Danemark] ; Stig E. Bojesen [Danemark] ; Charlotte Lanng [Danemark] ; Arto Mannermaa [Finlande] ; Vesa Kataja [Finlande] ; Veli-Matti Kosma [Finlande] ; Jaana M. Hartikainen [Finlande] ; Paolo Radice [Italie] ; Paolo Peterlongo [Italie] ; Siranoush Manoukian [Italie] ; Loris Bernard [Italie] ; Fergus J. Couch [États-Unis] ; Janet E. Olson [États-Unis] ; Xianshu Wang [États-Unis] ; Zachary Fredericksen [États-Unis] ; Grethe Grenaker Aln S [Norvège] ; Vessela Kristensen [Norvège] ; Anne-Lise B Rresen-Dale [Norvège] ; Peter Devilee [Pays-Bas] ; Robert A. E. M. Tollenaar [Pays-Bas] ; Caroline M. Seynaeve [Pays-Bas] ; Maartje J. Hooning [Pays-Bas] ; Montserrat García-Closas [Royaume-Uni] ; Stephen J. Chanock [États-Unis] ; Jolanta Lissowska [Pologne] ; Mark E. Sherman [États-Unis] ; Per Hall [Suède] ; Jianjun Liu [Suède] ; Kamila Czene [Suède] ; Daehee Kang [Corée du Sud] ; Keun-Young Yoo [Corée du Sud] ; Dong-Young Noh [Corée du Sud] ; Annika Lindblom [Suède] ; Sara Margolin [Suède] ; Alison M. Dunning [Royaume-Uni] ; Paul D. P. Pharoah [Royaume-Uni] ; Douglas F. Easton [Royaume-Uni] ; Pascal Guénel [France] ; Hiltrud Brauch [Allemagne]Source :
- Human Mutation [ 1059-7794 ] ; 2012-07.
Descripteurs français
- Wicri :
- geographic : Finlande.
- topic : Cancer, Consortium, épidémiologie, Génétique, Histologie, Recherche médicale, Médecine du travail, Oulu.
English descriptors
- KwdEn :
- Abcfs, Academia sinica, Accident insurance, Acute lymphoblastic leukaemia, Allele, Asian descent, Asian women, Association study, Bcac, Biocenter kuopio, Biomedical research centre, Biomedical sciences, Brca1, Brca1 mutations, Breakthrough breast cancer, Breakthrough breast cancer research centre, Breast, Breast cancer, Breast cancer association consortium, Breast cancer cases, Breast cancer family registry, Breast cancer patients, Breast cancer risk, Breast cancer susceptibility loci, Bsuch study, Cancer, Cancer care ontario, Cancer council victoria, Cancer epidemiology, Cancer foundation, Cancer genetics, Cancer institute, Cancer prevention institute, Cancer research, Cancer research centre, Cancer studies, Cecile study, Cell cycle control, Centre, Clin, Clin cancer, Clinical genetics, Clinical medicine, Clinical pharmacology, College london, Common variants, Consortium, Coriell institute, Coronary artery disease, Cyclin, Deutsche krebshilfe, Deutsches krebsforschungszentrum, Dkfz, Ductal, Dutch cancer society, Eastern finland, Epidemiol, Epidemiology, Erlangen, Estrogen, Estrogen breast cancer, Estrogen receptor, European descent, European women, Evangelische kliniken bonn ggmbh, Familial breast cancer risk, Family history, Federal ministry, Finland, Fondazione irccs istituto nazionale tumori, Forest plots, Foundation trust, Gene expression, General population, Genet, Genetic variants, Genetics, German cancer research center, Gwas, Heidelberg, Helmholtz society, Helsinki, Helsinki university, Herlev university hospital, Heterogeneity, Heterozygous, Hiltrud brauch, Histology, Histology ductal, Histopathological subtype, Homozygous effect, Horizontal lines, Hormone receptor status, Human cancer genetics programme, Human genetics, Human mutation, Inst, Internal medicine, Johanniter krankenhaus, Kuopio, Kuopio university hospital, Laboratory medicine, Leiden university, Lobular, Locus, Mammographic density, Many others, Mayo clinic, Medical research, Medical research council, Melbourne, Minor allele frequencies, Molecular epidemiology group, Molecular genetics, Molecular medicine, Mutation, National cancer institute, National health, Natl, Natl cancer inst, Nhmrc, Obstetrics, Occupational medicine, Odds ratio, Odds ratios, Ofbcr, Oncogenic driver, Oncology, Ontario, Ontario cancer genetics network, Other tumors, Oulu, Oulu university hospital, Ovarian cancer, Pancreatic cancer, Polymorphism, Postgraduate school, Receptor, Repair genes, Research centre, Sample sizes, Samuel lunenfeld research institute, Sigrid juselius foundation, Sinai hospital, Single nucleotide polymorphism, Snp, Study abcfs, Study participants, Subgroup analyses, Susceptibility, Tumor characteristics, Tumor subtype, Tumor subtypes, Turnbull, Ucibcs, University breast center, University hospital, University hospital erlangen, University tubingen, Unselected breast cancer patients, Variant, Victorian breast cancer research consortium group leader, Western australia, Wiley periodicals.
- Teeft :
- Abcfs, Academia sinica, Accident insurance, Acute lymphoblastic leukaemia, Allele, Asian descent, Asian women, Association study, Bcac, Biocenter kuopio, Biomedical research centre, Biomedical sciences, Brca1, Brca1 mutations, Breakthrough breast cancer, Breakthrough breast cancer research centre, Breast, Breast cancer, Breast cancer association consortium, Breast cancer cases, Breast cancer family registry, Breast cancer patients, Breast cancer risk, Breast cancer susceptibility loci, Bsuch study, Cancer, Cancer care ontario, Cancer council victoria, Cancer epidemiology, Cancer foundation, Cancer genetics, Cancer institute, Cancer prevention institute, Cancer research, Cancer research centre, Cancer studies, Cecile study, Cell cycle control, Centre, Clin, Clin cancer, Clinical genetics, Clinical medicine, Clinical pharmacology, College london, Common variants, Consortium, Coriell institute, Coronary artery disease, Cyclin, Deutsche krebshilfe, Deutsches krebsforschungszentrum, Dkfz, Ductal, Dutch cancer society, Eastern finland, Epidemiol, Epidemiology, Erlangen, Estrogen, Estrogen breast cancer, Estrogen receptor, European descent, European women, Evangelische kliniken bonn ggmbh, Familial breast cancer risk, Family history, Federal ministry, Finland, Fondazione irccs istituto nazionale tumori, Forest plots, Foundation trust, Gene expression, General population, Genet, Genetic variants, Genetics, German cancer research center, Gwas, Heidelberg, Helmholtz society, Helsinki, Helsinki university, Herlev university hospital, Heterogeneity, Heterozygous, Hiltrud brauch, Histology, Histology ductal, Histopathological subtype, Homozygous effect, Horizontal lines, Hormone receptor status, Human cancer genetics programme, Human genetics, Human mutation, Inst, Internal medicine, Johanniter krankenhaus, Kuopio, Kuopio university hospital, Laboratory medicine, Leiden university, Lobular, Locus, Mammographic density, Many others, Mayo clinic, Medical research, Medical research council, Melbourne, Minor allele frequencies, Molecular epidemiology group, Molecular genetics, Molecular medicine, Mutation, National cancer institute, National health, Natl, Natl cancer inst, Nhmrc, Obstetrics, Occupational medicine, Odds ratio, Odds ratios, Ofbcr, Oncogenic driver, Oncology, Ontario, Ontario cancer genetics network, Other tumors, Oulu, Oulu university hospital, Ovarian cancer, Pancreatic cancer, Polymorphism, Postgraduate school, Receptor, Repair genes, Research centre, Sample sizes, Samuel lunenfeld research institute, Sigrid juselius foundation, Sinai hospital, Single nucleotide polymorphism, Snp, Study abcfs, Study participants, Subgroup analyses, Susceptibility, Tumor characteristics, Tumor subtype, Tumor subtypes, Turnbull, Ucibcs, University breast center, University hospital, University hospital erlangen, University tubingen, Unselected breast cancer patients, Variant, Victorian breast cancer research consortium group leader, Western australia, Wiley periodicals.
Abstract
A recent two‐stage genome‐wide association study (GWAS) identified five novel breast cancer susceptibility loci on chromosomes 9, 10, and 11. To provide more reliable estimates of the relative risk associated with these loci and investigate possible heterogeneity by subtype of breast cancer, we genotyped the variants rs2380205, rs1011970, rs704010, rs614367, and rs10995190 in 39 studies from the Breast Cancer Association Consortium (BCAC), involving 49,608 cases and 48,772 controls of predominantly European ancestry. Four of the variants showed clear evidence of association (P ≤ 3 × 10−9) and weak evidence was observed for rs2380205 (P = 0.06). The strongest evidence was obtained for rs614367, located on 11q13 (per‐allele odds ratio 1.21, P = 4 × 10−39). The association for rs614367 was specific to estrogen receptor (ER)‐positive disease and strongest for ER plus progesterone receptor (PR)‐positive breast cancer, whereas the associations for the other three loci did not differ by tumor subtype. Hum Mutat 33:1123–1132, 2012. © 2012 Wiley Periodicals, Inc.
Url:
- https://api.istex.fr/document/CC63964BFBCF9F28F183C830DFC0B4DD9582A49D/fulltext/pdf
- http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3370081
DOI: 10.1002/humu.22089
Affiliations:
- Allemagne, Australie, Belgique, Biélorussie, Canada, Corée du Sud, Danemark, Espagne, Finlande, France, Irlande (pays), Italie, Norvège, Pays-Bas, Pologne, Royaume-Uni, Russie, Suède, Taïwan, Thaïlande, États-Unis
- Angleterre, Angleterre de l'Est, Bade-Wurtemberg, Basse-Saxe, Bavière, Californie, Communauté de Madrid, District de Cologne, District de Haute-Bavière, District de Karlsruhe, District de Moyenne-Franconie, District de Stuttgart, District de Tübingen, Grand Londres, Hambourg, Hollande-Méridionale, Hollande-Septentrionale, Hovedstaden, Lombardie, Maryland, Massachusetts, Minnesota, Ontario, Oxfordshire, Rhénanie-du-Nord-Westphalie, Région capitale de Séoul, Sarre (Land), Svealand, Victoria (État), Île-de-France, Østlandet
- Amsterdam, Bonn, Cambridge, Copenhague, Erlangen, Hambourg, Hanovre, Heidelberg, Leyde, Londres, Madrid, Melbourne, Milan, Munich, Oslo, Oxford, Rotterdam, Sarrebruck, Stockholm, Stuttgart, Séoul, Toronto, Tübingen, Ulm, Villejuif
- Université Louis-et-Maximilien de Munich, Université d'Oxford, Université d'Ulm, Université de Cambridge, Université de Melbourne, Université de Toronto
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Le document en format XML
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Andrulis</name></author><author><name sortKey="Selander, Teresa" sort="Selander, Teresa" uniqKey="Selander T" first="Teresa" last="Selander">Teresa Selander</name></author><author><name sortKey="Glendon, Gord" sort="Glendon, Gord" uniqKey="Glendon G" first="Gord" last="Glendon">Gord Glendon</name></author><author><name sortKey="Mulligan, Anna Marie" sort="Mulligan, Anna Marie" uniqKey="Mulligan A" first="Anna Marie" last="Mulligan">Anna Marie Mulligan</name></author><author><name sortKey="Anton Ulver, Hoda" sort="Anton Ulver, Hoda" uniqKey="Anton Ulver H" first="Hoda" last="Anton-Culver">Hoda Anton-Culver</name></author><author><name sortKey="Ziogas, Argyrios" sort="Ziogas, Argyrios" uniqKey="Ziogas A" first="Argyrios" last="Ziogas">Argyrios Ziogas</name></author><author><name sortKey="Muir, Kenneth R" sort="Muir, Kenneth R" uniqKey="Muir K" first="Kenneth R." last="Muir">Kenneth R. Muir</name></author><author><name sortKey="Lophatananon, Artitaya" sort="Lophatananon, Artitaya" uniqKey="Lophatananon A" first="Artitaya" last="Lophatananon">Artitaya Lophatananon</name></author><author><name sortKey="Rattanamongkongul, Suthee" sort="Rattanamongkongul, Suthee" uniqKey="Rattanamongkongul S" first="Suthee" last="Rattanamongkongul">Suthee Rattanamongkongul</name></author><author><name sortKey="Puttawibul, Puttisak" sort="Puttawibul, Puttisak" uniqKey="Puttawibul P" first="Puttisak" last="Puttawibul">Puttisak Puttawibul</name></author><author><name sortKey="Jones, Michael" sort="Jones, Michael" uniqKey="Jones M" first="Michael" last="Jones">Michael Jones</name></author><author><name sortKey="Orr, Nicholas" sort="Orr, Nicholas" uniqKey="Orr N" first="Nicholas" last="Orr">Nicholas Orr</name></author><author><name sortKey="Ashworth, Alan" sort="Ashworth, Alan" uniqKey="Ashworth A" first="Alan" last="Ashworth">Alan Ashworth</name></author><author><name sortKey="Swerdlow, Anthony" sort="Swerdlow, Anthony" uniqKey="Swerdlow A" first="Anthony" last="Swerdlow">Anthony Swerdlow</name></author><author><name sortKey="Severi, Gianluca" sort="Severi, Gianluca" uniqKey="Severi G" first="Gianluca" last="Severi">Gianluca Severi</name></author><author><name sortKey="Baglietto, Laura" sort="Baglietto, Laura" uniqKey="Baglietto L" first="Laura" last="Baglietto">Laura Baglietto</name></author><author><name sortKey="Giles, Graham" sort="Giles, Graham" uniqKey="Giles G" first="Graham" last="Giles">Graham Giles</name></author><author><name sortKey="Southey, Melissa" sort="Southey, Melissa" uniqKey="Southey M" first="Melissa" last="Southey">Melissa Southey</name></author><author><name sortKey="Marme, Federik" sort="Marme, Federik" uniqKey="Marme F" first="Federik" last="Marmé">Federik Marmé</name></author><author><name sortKey="Schneeweiss, Andreas" sort="Schneeweiss, Andreas" uniqKey="Schneeweiss A" first="Andreas" last="Schneeweiss">Andreas Schneeweiss</name></author><author><name sortKey="Sohn, Christof" sort="Sohn, Christof" uniqKey="Sohn C" first="Christof" last="Sohn">Christof Sohn</name></author><author><name sortKey="Burwinkel, Barbara" sort="Burwinkel, Barbara" uniqKey="Burwinkel B" first="Barbara" last="Burwinkel">Barbara Burwinkel</name></author><author><name sortKey="Yesilyurt, Betul T" sort="Yesilyurt, Betul T" uniqKey="Yesilyurt B" first="Betul T." last="Yesilyurt">Betul T. Yesilyurt</name></author><author><name sortKey="Neven, Patrick" sort="Neven, Patrick" uniqKey="Neven P" first="Patrick" last="Neven">Patrick Neven</name></author><author><name sortKey="Paridaens, Robert" sort="Paridaens, Robert" uniqKey="Paridaens R" first="Robert" last="Paridaens">Robert Paridaens</name></author><author><name sortKey="Wildiers, Hans" sort="Wildiers, Hans" uniqKey="Wildiers H" first="Hans" last="Wildiers">Hans Wildiers</name></author><author><name sortKey="Brenner, Hermann" sort="Brenner, Hermann" uniqKey="Brenner H" first="Hermann" last="Brenner">Hermann Brenner</name></author><author><name sortKey="Muller, Heiko" sort="Muller, Heiko" uniqKey="Muller H" first="Heiko" last="Müller">Heiko Müller</name></author><author><name sortKey="Arndt, Volker" sort="Arndt, Volker" uniqKey="Arndt V" first="Volker" last="Arndt">Volker Arndt</name></author><author><name sortKey="Stegmaier, Christa" sort="Stegmaier, Christa" uniqKey="Stegmaier C" first="Christa" last="Stegmaier">Christa Stegmaier</name></author><author><name sortKey="Meindl, Alfons" sort="Meindl, Alfons" uniqKey="Meindl A" first="Alfons" last="Meindl">Alfons Meindl</name></author><author><name sortKey="Schott, Sarah" sort="Schott, Sarah" uniqKey="Schott S" first="Sarah" last="Schott">Sarah Schott</name></author><author><name sortKey="Bartram, Claus R" sort="Bartram, Claus R" uniqKey="Bartram C" first="Claus R." last="Bartram">Claus R. Bartram</name></author><author><name sortKey="Schmutzler, Rita K" sort="Schmutzler, Rita K" uniqKey="Schmutzler R" first="Rita K." last="Schmutzler">Rita K. Schmutzler</name></author><author><name sortKey="Cox, Angela" sort="Cox, Angela" uniqKey="Cox A" first="Angela" last="Cox">Angela Cox</name></author><author><name sortKey="Brock, Ian W" sort="Brock, Ian W" uniqKey="Brock I" first="Ian W." last="Brock">Ian W. Brock</name></author><author><name sortKey="Elliott, Graeme" sort="Elliott, Graeme" uniqKey="Elliott G" first="Graeme" last="Elliott">Graeme Elliott</name></author><author><name sortKey="Cross, Simon S" sort="Cross, Simon S" uniqKey="Cross S" first="Simon S." last="Cross">Simon S. Cross</name></author><author><name sortKey="Fasching, Peter A" sort="Fasching, Peter A" uniqKey="Fasching P" first="Peter A." last="Fasching">Peter A. Fasching</name></author><author><name sortKey="Schulz Endtland, Ruediger" sort="Schulz Endtland, Ruediger" uniqKey="Schulz Endtland R" first="Ruediger" last="Schulz-Wendtland">Ruediger Schulz-Wendtland</name></author><author><name sortKey="Ekici, Arif B" sort="Ekici, Arif B" uniqKey="Ekici A" first="Arif B." last="Ekici">Arif B. Ekici</name></author><author><name sortKey="Beckmann, Matthias W" sort="Beckmann, Matthias W" uniqKey="Beckmann M" first="Matthias W." last="Beckmann">Matthias W. Beckmann</name></author><author><name sortKey="Fletcher, Olivia" sort="Fletcher, Olivia" uniqKey="Fletcher O" first="Olivia" last="Fletcher">Olivia Fletcher</name></author><author><name sortKey="Johnson, Nichola" sort="Johnson, Nichola" uniqKey="Johnson N" first="Nichola" last="Johnson">Nichola Johnson</name></author><author><name sortKey="Silva, Isabel Dos Santos" sort="Silva, Isabel Dos Santos" uniqKey="Silva I" first="Isabel Dos Santos" last="Silva">Isabel Dos Santos Silva</name></author><author><name sortKey="Peto, Julian" sort="Peto, Julian" uniqKey="Peto J" first="Julian" last="Peto">Julian Peto</name></author><author><name sortKey="Nevanlinna, Heli" sort="Nevanlinna, Heli" uniqKey="Nevanlinna H" first="Heli" last="Nevanlinna">Heli Nevanlinna</name></author><author><name sortKey="Muranen, Taru A" sort="Muranen, Taru A" uniqKey="Muranen T" first="Taru A." last="Muranen">Taru A. Muranen</name></author><author><name sortKey="Aittom Ki, Kristiina" sort="Aittom Ki, Kristiina" uniqKey="Aittom Ki K" first="Kristiina" last="Aittom Ki">Kristiina Aittom Ki</name></author><author><name sortKey="Blomqvist, Carl" sort="Blomqvist, Carl" uniqKey="Blomqvist C" first="Carl" last="Blomqvist">Carl Blomqvist</name></author><author><name sortKey="Dork, Thilo" sort="Dork, Thilo" uniqKey="Dork T" first="Thilo" last="Dörk">Thilo Dörk</name></author><author><name sortKey="Schurmann, Peter" sort="Schurmann, Peter" uniqKey="Schurmann P" first="Peter" last="Schürmann">Peter Schürmann</name></author><author><name sortKey="Bremer, Michael" sort="Bremer, Michael" uniqKey="Bremer M" first="Michael" last="Bremer">Michael Bremer</name></author><author><name sortKey="Hillemanns, Peter" sort="Hillemanns, Peter" uniqKey="Hillemanns P" first="Peter" last="Hillemanns">Peter Hillemanns</name></author><author><name sortKey="Bogdanova, Natalia V" sort="Bogdanova, Natalia V" uniqKey="Bogdanova N" first="Natalia V." last="Bogdanova">Natalia V. Bogdanova</name></author><author><name sortKey="Antonenkova, Natalia N" sort="Antonenkova, Natalia N" uniqKey="Antonenkova N" first="Natalia N." last="Antonenkova">Natalia N. Antonenkova</name></author><author><name sortKey="Rogov, Yuri I" sort="Rogov, Yuri I" uniqKey="Rogov Y" first="Yuri I." last="Rogov">Yuri I. Rogov</name></author><author><name sortKey="Karstens, Johann H" sort="Karstens, Johann H" uniqKey="Karstens J" first="Johann H." last="Karstens">Johann H. Karstens</name></author><author><name sortKey="Khusnutdinova, Elza" sort="Khusnutdinova, Elza" uniqKey="Khusnutdinova E" first="Elza" last="Khusnutdinova">Elza Khusnutdinova</name></author><author><name sortKey="Bermisheva, Marina" sort="Bermisheva, Marina" uniqKey="Bermisheva M" first="Marina" last="Bermisheva">Marina Bermisheva</name></author><author><name sortKey="Prokofieva, Darya" sort="Prokofieva, Darya" uniqKey="Prokofieva D" first="Darya" last="Prokofieva">Darya Prokofieva</name></author><author><name sortKey="Gancev, Shamil" sort="Gancev, Shamil" uniqKey="Gancev S" first="Shamil" last="Gancev">Shamil Gancev</name></author><author><name sortKey="Jakubowska, Anna" sort="Jakubowska, Anna" uniqKey="Jakubowska A" first="Anna" last="Jakubowska">Anna Jakubowska</name></author><author><name sortKey="Lubinski, Jan" sort="Lubinski, Jan" uniqKey="Lubinski J" first="Jan" last="Lubinski">Jan Lubinski</name></author><author><name sortKey="Jaworska, Katarzyna" sort="Jaworska, Katarzyna" uniqKey="Jaworska K" first="Katarzyna" last="Jaworska">Katarzyna Jaworska</name></author><author><name sortKey="Durda, Katarzyna" sort="Durda, Katarzyna" uniqKey="Durda K" first="Katarzyna" last="Durda">Katarzyna Durda</name></author><author><name sortKey="Nordestgaard, B Rge G" sort="Nordestgaard, B Rge G" uniqKey="Nordestgaard B" first="B Rge G." last="Nordestgaard">B Rge G. Nordestgaard</name></author><author><name sortKey="Bojesen, Stig E" sort="Bojesen, Stig E" uniqKey="Bojesen S" first="Stig E." last="Bojesen">Stig E. Bojesen</name></author><author><name sortKey="Lanng, Charlotte" sort="Lanng, Charlotte" uniqKey="Lanng C" first="Charlotte" last="Lanng">Charlotte Lanng</name></author><author><name sortKey="Mannermaa, Arto" sort="Mannermaa, Arto" uniqKey="Mannermaa A" first="Arto" last="Mannermaa">Arto Mannermaa</name></author><author><name sortKey="Kataja, Vesa" sort="Kataja, Vesa" uniqKey="Kataja V" first="Vesa" last="Kataja">Vesa Kataja</name></author><author><name sortKey="Kosma, Veli Atti" sort="Kosma, Veli Atti" uniqKey="Kosma V" first="Veli-Matti" last="Kosma">Veli-Matti Kosma</name></author><author><name sortKey="Hartikainen, Jaana M" sort="Hartikainen, Jaana M" uniqKey="Hartikainen J" first="Jaana M." last="Hartikainen">Jaana M. Hartikainen</name></author><author><name sortKey="Radice, Paolo" sort="Radice, Paolo" uniqKey="Radice P" first="Paolo" last="Radice">Paolo Radice</name></author><author><name sortKey="Peterlongo, Paolo" sort="Peterlongo, Paolo" uniqKey="Peterlongo P" first="Paolo" last="Peterlongo">Paolo Peterlongo</name></author><author><name sortKey="Manoukian, Siranoush" sort="Manoukian, Siranoush" uniqKey="Manoukian S" first="Siranoush" last="Manoukian">Siranoush Manoukian</name></author><author><name sortKey="Bernard, Loris" sort="Bernard, Loris" uniqKey="Bernard L" first="Loris" last="Bernard">Loris Bernard</name></author><author><name sortKey="Couch, Fergus J" sort="Couch, Fergus J" uniqKey="Couch F" first="Fergus J." last="Couch">Fergus J. Couch</name></author><author><name sortKey="Olson, Janet E" sort="Olson, Janet E" uniqKey="Olson J" first="Janet E." last="Olson">Janet E. Olson</name></author><author><name sortKey="Wang, Xianshu" sort="Wang, Xianshu" uniqKey="Wang X" first="Xianshu" last="Wang">Xianshu Wang</name></author><author><name sortKey="Fredericksen, Zachary" sort="Fredericksen, Zachary" uniqKey="Fredericksen Z" first="Zachary" last="Fredericksen">Zachary Fredericksen</name></author><author><name sortKey="Aln S, Grethe Grenaker" sort="Aln S, Grethe Grenaker" uniqKey="Aln S G" first="Grethe Grenaker" last="Aln S">Grethe Grenaker Aln S</name></author><author><name sortKey="Kristensen, Vessela" sort="Kristensen, Vessela" uniqKey="Kristensen V" first="Vessela" last="Kristensen">Vessela Kristensen</name></author><author><name sortKey="B Rresen Ale, Anne Ise" sort="B Rresen Ale, Anne Ise" uniqKey="B Rresen Ale A" first="Anne-Lise" last="B Rresen-Dale">Anne-Lise B Rresen-Dale</name></author><author><name sortKey="Devilee, Peter" sort="Devilee, Peter" uniqKey="Devilee P" first="Peter" last="Devilee">Peter Devilee</name></author><author><name sortKey="Tollenaar, Robert A E M" sort="Tollenaar, Robert A E M" uniqKey="Tollenaar R" first="Robert A. E. M." last="Tollenaar">Robert A. E. M. Tollenaar</name></author><author><name sortKey="Seynaeve, Caroline M" sort="Seynaeve, Caroline M" uniqKey="Seynaeve C" first="Caroline M." last="Seynaeve">Caroline M. Seynaeve</name></author><author><name sortKey="Hooning, Maartje J" sort="Hooning, Maartje J" uniqKey="Hooning M" first="Maartje J." last="Hooning">Maartje J. Hooning</name></author><author><name sortKey="Garcia Losas, Montserrat" sort="Garcia Losas, Montserrat" uniqKey="Garcia Losas M" first="Montserrat" last="García-Closas">Montserrat García-Closas</name></author><author><name sortKey="Chanock, Stephen J" sort="Chanock, Stephen J" uniqKey="Chanock S" first="Stephen J." last="Chanock">Stephen J. Chanock</name></author><author><name sortKey="Lissowska, Jolanta" sort="Lissowska, Jolanta" uniqKey="Lissowska J" first="Jolanta" last="Lissowska">Jolanta Lissowska</name></author><author><name sortKey="Sherman, Mark E" sort="Sherman, Mark E" uniqKey="Sherman M" first="Mark E." last="Sherman">Mark E. Sherman</name></author><author><name sortKey="Hall, Per" sort="Hall, Per" uniqKey="Hall P" first="Per" last="Hall">Per Hall</name></author><author><name sortKey="Liu, Jianjun" sort="Liu, Jianjun" uniqKey="Liu J" first="Jianjun" last="Liu">Jianjun Liu</name></author><author><name sortKey="Czene, Kamila" sort="Czene, Kamila" uniqKey="Czene K" first="Kamila" last="Czene">Kamila Czene</name></author><author><name sortKey="Kang, Daehee" sort="Kang, Daehee" uniqKey="Kang D" first="Daehee" last="Kang">Daehee Kang</name></author><author><name sortKey="Yoo, Keun Oung" sort="Yoo, Keun Oung" uniqKey="Yoo K" first="Keun-Young" last="Yoo">Keun-Young Yoo</name></author><author><name sortKey="Noh, Dong Oung" sort="Noh, Dong Oung" uniqKey="Noh D" first="Dong-Young" last="Noh">Dong-Young Noh</name></author><author><name sortKey="Lindblom, Annika" sort="Lindblom, Annika" uniqKey="Lindblom A" first="Annika" last="Lindblom">Annika Lindblom</name></author><author><name sortKey="Margolin, Sara" sort="Margolin, Sara" uniqKey="Margolin S" first="Sara" last="Margolin">Sara Margolin</name></author><author><name sortKey="Dunning, Alison M" sort="Dunning, Alison M" uniqKey="Dunning A" first="Alison M." last="Dunning">Alison M. Dunning</name></author><author><name sortKey="Pharoah, Paul D P" sort="Pharoah, Paul D P" uniqKey="Pharoah P" first="Paul D. P." last="Pharoah">Paul D. P. Pharoah</name></author><author><name sortKey="Easton, Douglas F" sort="Easton, Douglas F" uniqKey="Easton D" first="Douglas F." last="Easton">Douglas F. Easton</name></author><author><name sortKey="Guenel, Pascal" sort="Guenel, Pascal" uniqKey="Guenel P" first="Pascal" last="Guénel">Pascal Guénel</name></author><author><name sortKey="Brauch, Hiltrud" sort="Brauch, Hiltrud" uniqKey="Brauch H" first="Hiltrud" last="Brauch">Hiltrud Brauch</name></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:CC63964BFBCF9F28F183C830DFC0B4DD9582A49D</idno><date when="2012" year="2012">2012</date><idno type="doi">10.1002/humu.22089</idno><idno type="url">https://api.istex.fr/document/CC63964BFBCF9F28F183C830DFC0B4DD9582A49D/fulltext/pdf</idno><idno type="wicri:Area/Istex/Corpus">002611</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Corpus" wicri:corpus="ISTEX">002611</idno><idno type="wicri:Area/Istex/Curation">002611</idno><idno type="wicri:Area/Istex/Checkpoint">000668</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Checkpoint">000668</idno><idno type="wicri:doubleKey">1059-7794:2012:Lambrechts D:q:is:a</idno><idno type="wicri:source">PMC</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3370081</idno><idno type="RBID">PMC:3370081</idno><idno type="wicri:Area/Pmc/Corpus">002108</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">002108</idno><idno type="wicri:Area/Pmc/Curation">001F62</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">001F62</idno><idno type="wicri:Area/Pmc/Checkpoint">002117</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">002117</idno><idno type="wicri:Area/Ncbi/Merge">000D63</idno><idno type="wicri:Area/Ncbi/Curation">000D63</idno><idno type="wicri:Area/Ncbi/Checkpoint">000D63</idno><idno type="wicri:doubleKey">1059-7794:2012:Lambrechts D:q:is:a</idno><idno type="wicri:Area/Main/Merge">005A10</idno><idno type="wicri:Area/Main/Curation">005743</idno><idno type="wicri:Area/Main/Exploration">005743</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">11q13 is a susceptibility locus for hormone receptor positive breast cancer<ref type="note" target="#fn1"></ref></title><author><name sortKey="Lambrechts, Diether" sort="Lambrechts, Diether" uniqKey="Lambrechts D" first="Diether" last="Lambrechts">Diether Lambrechts</name><affiliation wicri:level="1"><country xml:lang="fr">Belgique</country><wicri:regionArea>Vesalius Research Center (VRC), VIB, KU Leuven, Leuven</wicri:regionArea><wicri:noRegion>Leuven</wicri:noRegion></affiliation></author><author><name sortKey="Truong, Therese" sort="Truong, Therese" uniqKey="Truong T" first="Therese" last="Truong">Therese Truong</name><affiliation wicri:level="3"><country xml:lang="fr">France</country><wicri:regionArea>Environmental Epidemiology of Cancer, CESP Centre for Research in Epidemiology and Population Health, U1018, Inserm, F‐94807, Villejuif</wicri:regionArea><placeName><region type="region" nuts="2">Île-de-France</region><settlement type="city">Villejuif</settlement></placeName></affiliation><affiliation wicri:level="1"><country xml:lang="fr">France</country><wicri:regionArea>University Paris‐Sud, UMRS 1018, Villejuif</wicri:regionArea><wicri:noRegion>Villejuif</wicri:noRegion><wicri:noRegion>Villejuif</wicri:noRegion></affiliation></author><author><name sortKey="Justenhoven, Christina" sort="Justenhoven, Christina" uniqKey="Justenhoven C" first="Christina" last="Justenhoven">Christina Justenhoven</name><affiliation wicri:level="3"><country xml:lang="fr">Allemagne</country><wicri:regionArea>Dr. Margarete Fischer‐Bosch‐Institute of Clinical Pharmacology, Stuttgart; University Tübingen, Tübingen</wicri:regionArea><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Tübingen</region><settlement type="city">Tübingen</settlement></placeName></affiliation></author><author><name sortKey="Humphreys, Manjeet K" sort="Humphreys, Manjeet K" uniqKey="Humphreys M" first="Manjeet K." last="Humphreys">Manjeet K. Humphreys</name><affiliation wicri:level="4"><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge</wicri:regionArea><orgName type="university">Université de Cambridge</orgName><placeName><settlement type="city">Cambridge</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Angleterre de l'Est</region></placeName></affiliation></author><author><name sortKey="Wang, Jean" sort="Wang, Jean" uniqKey="Wang J" first="Jean" last="Wang">Jean Wang</name><affiliation wicri:level="4"><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge</wicri:regionArea><orgName type="university">Université de Cambridge</orgName><placeName><settlement type="city">Cambridge</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Angleterre de l'Est</region></placeName></affiliation></author><author><name sortKey="Hopper, John L" sort="Hopper, John L" uniqKey="Hopper J" first="John L." last="Hopper">John L. Hopper</name><affiliation wicri:level="4"><country xml:lang="fr">Australie</country><wicri:regionArea>Centre for Molecular, Environmental, Genetic and Analytic Epidemiology, The University of Melbourne, Melbourne</wicri:regionArea><placeName><settlement type="city">Melbourne</settlement><region type="état">Victoria (État)</region><settlement type="city">Melbourne</settlement></placeName><orgName type="university">Université de Melbourne</orgName></affiliation></author><author><name sortKey="Dite, Gillian S" sort="Dite, Gillian S" uniqKey="Dite G" first="Gillian S." last="Dite">Gillian S. Dite</name><affiliation wicri:level="4"><country xml:lang="fr">Australie</country><wicri:regionArea>Centre for Molecular, Environmental, Genetic and Analytic Epidemiology, The University of Melbourne, Melbourne</wicri:regionArea><placeName><settlement type="city">Melbourne</settlement><region type="état">Victoria (État)</region><settlement type="city">Melbourne</settlement></placeName><orgName type="university">Université de Melbourne</orgName></affiliation></author><author><name sortKey="Apicella, Carmel" sort="Apicella, Carmel" uniqKey="Apicella C" first="Carmel" last="Apicella">Carmel Apicella</name><affiliation wicri:level="4"><country xml:lang="fr">Australie</country><wicri:regionArea>Centre for Molecular, Environmental, Genetic and Analytic Epidemiology, The University of Melbourne, Melbourne</wicri:regionArea><placeName><settlement type="city">Melbourne</settlement><region type="état">Victoria (État)</region><settlement type="city">Melbourne</settlement></placeName><orgName type="university">Université de Melbourne</orgName></affiliation></author><author><name sortKey="Southey, Melissa C" sort="Southey, Melissa C" uniqKey="Southey M" first="Melissa C." last="Southey">Melissa C. Southey</name><affiliation wicri:level="4"><country xml:lang="fr">Australie</country><wicri:regionArea>Department of Pathology, The University of Melbourne, Melbourne</wicri:regionArea><placeName><settlement type="city">Melbourne</settlement><region type="état">Victoria (État)</region><settlement type="city">Melbourne</settlement></placeName><orgName type="university">Université de Melbourne</orgName></affiliation></author><author><name sortKey="Schmidt, Marjanka K" sort="Schmidt, Marjanka K" uniqKey="Schmidt M" first="Marjanka K." last="Schmidt">Marjanka K. Schmidt</name><affiliation wicri:level="3"><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Netherlands Cancer Institute ‐ Antoni van Leeuwenhoek Hospital, Amsterdam</wicri:regionArea><placeName><settlement type="city">Amsterdam</settlement><region nuts="2" type="province">Hollande-Septentrionale</region></placeName></affiliation></author><author><name sortKey="Broeks, Annegien" sort="Broeks, Annegien" uniqKey="Broeks A" first="Annegien" last="Broeks">Annegien Broeks</name><affiliation wicri:level="3"><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Netherlands Cancer Institute ‐ Antoni van Leeuwenhoek Hospital, Amsterdam</wicri:regionArea><placeName><settlement type="city">Amsterdam</settlement><region nuts="2" type="province">Hollande-Septentrionale</region></placeName></affiliation></author><author><name sortKey="Cornelissen, Sten" sort="Cornelissen, Sten" uniqKey="Cornelissen S" first="Sten" last="Cornelissen">Sten Cornelissen</name><affiliation wicri:level="3"><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Netherlands Cancer Institute ‐ Antoni van Leeuwenhoek Hospital, Amsterdam</wicri:regionArea><placeName><settlement type="city">Amsterdam</settlement><region nuts="2" type="province">Hollande-Septentrionale</region></placeName></affiliation></author><author><name sortKey="Van Hien, Richard" sort="Van Hien, Richard" uniqKey="Van Hien R" first="Richard" last="Van Hien">Richard Van Hien</name><affiliation wicri:level="3"><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Netherlands Cancer Institute ‐ Antoni van Leeuwenhoek Hospital, Amsterdam</wicri:regionArea><placeName><settlement type="city">Amsterdam</settlement><region nuts="2" type="province">Hollande-Septentrionale</region></placeName></affiliation></author><author><name sortKey="Sawyer, Elinor" sort="Sawyer, Elinor" uniqKey="Sawyer E" first="Elinor" last="Sawyer">Elinor Sawyer</name><affiliation wicri:level="3"><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Division of Cancer Studies, NIHR Comprehensive Biomedical Research Centre, Guy's and St. Thomas' NHS Foundation Trust in partnership with King's College London, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Tomlinson, Ian" sort="Tomlinson, Ian" uniqKey="Tomlinson I" first="Ian" last="Tomlinson">Ian Tomlinson</name><affiliation wicri:level="4"><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Welcome Trust Centre for Human Genetics and Oxford Biomedical Research Centre, University of Oxford</wicri:regionArea><placeName><settlement type="city">Oxford</settlement><region type="nation">Angleterre</region><region type="région" nuts="1">Oxfordshire</region></placeName><orgName type="university">Université d'Oxford</orgName></affiliation></author><author><name sortKey="Kerin, Michael" sort="Kerin, Michael" uniqKey="Kerin M" first="Michael" last="Kerin">Michael Kerin</name><affiliation wicri:level="1"><country xml:lang="fr">Irlande (pays)</country><wicri:regionArea>Clinical Science Institute. University Hospital Galway, Galway</wicri:regionArea><wicri:noRegion>Galway</wicri:noRegion></affiliation></author><author><name sortKey="Miller, Nicola" sort="Miller, Nicola" uniqKey="Miller N" first="Nicola" last="Miller">Nicola Miller</name><affiliation wicri:level="1"><country xml:lang="fr">Irlande (pays)</country><wicri:regionArea>Clinical Science Institute. University Hospital Galway, Galway</wicri:regionArea><wicri:noRegion>Galway</wicri:noRegion></affiliation></author><author><name sortKey="Milne, Roger L" sort="Milne, Roger L" uniqKey="Milne R" first="Roger L." last="Milne">Roger L. Milne</name><affiliation wicri:level="3"><country xml:lang="fr">Espagne</country><wicri:regionArea>Genetic and Molecular Epidemiology Group, Human Cancer Genetics Programme, Spanish National Cancer Research Centre (CNIO), Madrid</wicri:regionArea><placeName><settlement type="city">Madrid</settlement><region nuts="2" type="region">Communauté de Madrid</region></placeName></affiliation></author><author><name sortKey="Zamora, M Pilar" sort="Zamora, M Pilar" uniqKey="Zamora M" first="M. Pilar" last="Zamora">M. Pilar Zamora</name><affiliation wicri:level="3"><country xml:lang="fr">Espagne</country><wicri:regionArea>Servicio de Oncología Médica, Hospital Universitario La Paz, Madrid</wicri:regionArea><placeName><settlement type="city">Madrid</settlement><region nuts="2" type="region">Communauté de Madrid</region></placeName></affiliation></author><author><name sortKey="Perez, Jose Ignacio Arias" sort="Perez, Jose Ignacio Arias" uniqKey="Perez J" first="José Ignacio Arias" last="Pérez">José Ignacio Arias Pérez</name><affiliation wicri:level="1"><country xml:lang="fr">Espagne</country><wicri:regionArea>Servicio de Cirugía General y Especialidades, Hospital Monte Naranco, Oviedo</wicri:regionArea><wicri:noRegion>Oviedo</wicri:noRegion></affiliation></author><author><name sortKey="Benitez, Javier" sort="Benitez, Javier" uniqKey="Benitez J" first="Javier" last="Benítez">Javier Benítez</name><affiliation wicri:level="3"><country xml:lang="fr">Espagne</country><wicri:regionArea>Human Genetics Group, Human Cancer Genetics Programme, Spanish National Cancer Research Centre (CNIO), Madrid</wicri:regionArea><placeName><settlement type="city">Madrid</settlement><region nuts="2" type="region">Communauté de Madrid</region></placeName></affiliation></author><author><name sortKey="Hamann, Ute" sort="Hamann, Ute" uniqKey="Hamann U" first="Ute" last="Hamann">Ute Hamann</name><affiliation wicri:level="3"><country xml:lang="fr">Allemagne</country><wicri:regionArea>Molecular Genetics of Breast Cancer, Deutsches Krebsforschungszentrum (DKFZ), Heidelberg</wicri:regionArea><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Karlsruhe</region><settlement type="city">Heidelberg</settlement></placeName></affiliation></author><author><name sortKey="Ko, Yon Schun" sort="Ko, Yon Schun" uniqKey="Ko Y" first="Yon-Dschun" last="Ko">Yon-Dschun Ko</name><affiliation wicri:level="3"><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Internal Medicine, Evangelische Kliniken Bonn gGmbH, Johanniter Krankenhaus, Bonn</wicri:regionArea><placeName><region type="land" nuts="1">Rhénanie-du-Nord-Westphalie</region><region type="district" nuts="2">District de Cologne</region><settlement type="city">Bonn</settlement></placeName></affiliation></author><author><name sortKey="Bruning, Thomas" sort="Bruning, Thomas" uniqKey="Bruning T" first="Thomas" last="Brüning">Thomas Brüning</name><affiliation wicri:level="1"><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute for Prevention and Occupational Medicine of the German Social Accident Insurance (IPA), Bochum</wicri:regionArea><wicri:noRegion>Bochum</wicri:noRegion><wicri:noRegion>Bochum</wicri:noRegion></affiliation></author><author><name sortKey="Chang Laude, Jenny" sort="Chang Laude, Jenny" uniqKey="Chang Laude J" first="Jenny" last="Chang-Claude">Jenny Chang-Claude</name><affiliation wicri:level="3"><country xml:lang="fr">Allemagne</country><wicri:regionArea>Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg</wicri:regionArea><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Karlsruhe</region><settlement type="city">Heidelberg</settlement></placeName></affiliation></author><author><name sortKey="Eilber, Ursel" sort="Eilber, Ursel" uniqKey="Eilber U" first="Ursel" last="Eilber">Ursel Eilber</name><affiliation wicri:level="3"><country xml:lang="fr">Allemagne</country><wicri:regionArea>Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg</wicri:regionArea><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Karlsruhe</region><settlement type="city">Heidelberg</settlement></placeName></affiliation></author><author><name sortKey="Hein, Rebecca" sort="Hein, Rebecca" uniqKey="Hein R" first="Rebecca" last="Hein">Rebecca Hein</name><affiliation wicri:level="3"><country xml:lang="fr">Allemagne</country><wicri:regionArea>Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg</wicri:regionArea><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Karlsruhe</region><settlement type="city">Heidelberg</settlement></placeName></affiliation></author><author><name sortKey="Nickels, Stefan" sort="Nickels, Stefan" uniqKey="Nickels S" first="Stefan" last="Nickels">Stefan Nickels</name><affiliation wicri:level="3"><country xml:lang="fr">Allemagne</country><wicri:regionArea>Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg</wicri:regionArea><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Karlsruhe</region><settlement type="city">Heidelberg</settlement></placeName></affiliation></author><author><name sortKey="Flesch Anys, Dieter" sort="Flesch Anys, Dieter" uniqKey="Flesch Anys D" first="Dieter" last="Flesch-Janys">Dieter Flesch-Janys</name><affiliation wicri:level="3"><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute for Medical Biometrics and Epidemiology, University Clinic Hamburg‐Eppendorf, Hamburg</wicri:regionArea><placeName><settlement type="city">Hambourg</settlement><region type="land" nuts="2">Hambourg</region></placeName></affiliation></author><author><name sortKey="Wang Ohrke, Shan" sort="Wang Ohrke, Shan" uniqKey="Wang Ohrke S" first="Shan" last="Wang-Gohrke">Shan Wang-Gohrke</name><affiliation wicri:level="4"><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Obstetrics and Gynecology, University of Ulm, Ulm</wicri:regionArea><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Tübingen</region><settlement type="city">Ulm</settlement><settlement type="city">Ulm</settlement></placeName><orgName type="university">Université d'Ulm</orgName></affiliation></author><author><name sortKey="John, Esther M" sort="John, Esther M" uniqKey="John E" first="Esther M." last="John">Esther M. John</name><affiliation wicri:level="2"><country>États-Unis</country><placeName><region type="state">Californie</region></placeName><wicri:cityArea>Cancer Prevention Institute of California, Fremont, California and Stanford University School of Medicine and Stanford Cancer Institute, Stanford</wicri:cityArea></affiliation></author><author><name sortKey="Miron, Alexander" sort="Miron, Alexander" uniqKey="Miron A" first="Alexander" last="Miron">Alexander Miron</name><affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country><placeName><region type="state">Massachusetts</region></placeName><wicri:cityArea>Dana‐Farber Cancer Institute, Boston</wicri:cityArea></affiliation></author><author><name sortKey="Winqvist, Robert" sort="Winqvist, Robert" uniqKey="Winqvist R" first="Robert" last="Winqvist">Robert Winqvist</name><affiliation wicri:level="1"><country xml:lang="fr">Finlande</country><wicri:regionArea>Laboratory of Cancer Genetics, Department of Clinical Genetics and Biocenter Oulu, University of Oulu, Oulu</wicri:regionArea><wicri:noRegion>Oulu</wicri:noRegion></affiliation></author><author><name sortKey="Pylk S, Katri" sort="Pylk S, Katri" uniqKey="Pylk S K" first="Katri" last="Pylk S">Katri Pylk S</name><affiliation wicri:level="1"><country xml:lang="fr">Finlande</country><wicri:regionArea>Laboratory of Cancer Genetics, Department of Clinical Genetics and Biocenter Oulu, University of Oulu, Oulu</wicri:regionArea><wicri:noRegion>Oulu</wicri:noRegion></affiliation></author><author><name sortKey="Jukkola Uorinen, Arja" sort="Jukkola Uorinen, Arja" uniqKey="Jukkola Uorinen A" first="Arja" last="Jukkola-Vuorinen">Arja Jukkola-Vuorinen</name><affiliation wicri:level="1"><country xml:lang="fr">Finlande</country><wicri:regionArea>Department of Oncology, Oulu University Hospital, University of Oulu, Oulu</wicri:regionArea><wicri:noRegion>Oulu</wicri:noRegion></affiliation></author><author><name sortKey="Grip, Mervi" sort="Grip, Mervi" uniqKey="Grip M" first="Mervi" last="Grip">Mervi Grip</name><affiliation wicri:level="1"><country xml:lang="fr">Finlande</country><wicri:regionArea>Department of Surgery, Oulu University Hospital, University of Oulu, Oulu</wicri:regionArea><wicri:noRegion>Oulu</wicri:noRegion></affiliation></author><author><name sortKey="Chenevix Rench, Georgia" sort="Chenevix Rench, Georgia" uniqKey="Chenevix Rench G" first="Georgia" last="Chenevix-Trench">Georgia Chenevix-Trench</name><affiliation wicri:level="1"><country xml:lang="fr">Australie</country><wicri:regionArea>Queensland Institute of Medical Research, Brisbane</wicri:regionArea><wicri:noRegion>Brisbane</wicri:noRegion></affiliation></author><author><name sortKey="Beesley, Jonathan" sort="Beesley, Jonathan" uniqKey="Beesley J" first="Jonathan" last="Beesley">Jonathan Beesley</name><affiliation wicri:level="1"><country xml:lang="fr">Australie</country><wicri:regionArea>Queensland Institute of Medical Research, Brisbane</wicri:regionArea><wicri:noRegion>Brisbane</wicri:noRegion></affiliation></author><author><name sortKey="Chen, Xiaoqing" sort="Chen, Xiaoqing" uniqKey="Chen X" first="Xiaoqing" last="Chen">Xiaoqing Chen</name><affiliation wicri:level="1"><country xml:lang="fr">Australie</country><wicri:regionArea>Queensland Institute of Medical Research, Brisbane</wicri:regionArea><wicri:noRegion>Brisbane</wicri:noRegion></affiliation></author><author><name sortKey="Investigators, Kconfab" sort="Investigators, Kconfab" uniqKey="Investigators K" first="Kconfab" last="Investigators">Kconfab Investigators</name><affiliation wicri:level="3"><country xml:lang="fr">Australie</country><wicri:regionArea>Peter MacCallum Cancer Center, Melbourne</wicri:regionArea><placeName><settlement type="city">Melbourne</settlement><region type="état">Victoria (État)</region></placeName></affiliation></author><author><name sortKey="Menegaux, Florence" sort="Menegaux, Florence" uniqKey="Menegaux F" first="Florence" last="Menegaux">Florence Menegaux</name><affiliation wicri:level="1"><country xml:lang="fr">France</country><wicri:regionArea>Environmental Epidemiology of Cancer, CESP Centre for Research in Epidemiology and Population Health, U1018, Inserm, F‐94807, Villejuif</wicri:regionArea><wicri:noRegion>94807, Villejuif</wicri:noRegion><wicri:noRegion>Villejuif</wicri:noRegion></affiliation><affiliation wicri:level="1"><country xml:lang="fr">France</country><wicri:regionArea>University Paris‐Sud, UMRS 1018, Villejuif</wicri:regionArea><wicri:noRegion>Villejuif</wicri:noRegion><wicri:noRegion>Villejuif</wicri:noRegion></affiliation></author><author><name sortKey="Cordina Uverger, Emilie" sort="Cordina Uverger, Emilie" uniqKey="Cordina Uverger E" first="Emilie" last="Cordina-Duverger">Emilie Cordina-Duverger</name><affiliation wicri:level="3"><country xml:lang="fr">France</country><wicri:regionArea>Environmental Epidemiology of Cancer, CESP Centre for Research in Epidemiology and Population Health, U1018, Inserm, F‐94807, Villejuif</wicri:regionArea><placeName><region type="region" nuts="2">Île-de-France</region><settlement type="city">Villejuif</settlement></placeName></affiliation><affiliation wicri:level="1"><country xml:lang="fr">France</country><wicri:regionArea>University Paris‐Sud, UMRS 1018, Villejuif</wicri:regionArea><wicri:noRegion>Villejuif</wicri:noRegion><wicri:noRegion>Villejuif</wicri:noRegion></affiliation></author><author><name sortKey="Shen, Chen Ang" sort="Shen, Chen Ang" uniqKey="Shen C" first="Chen-Yang" last="Shen">Chen-Yang Shen</name><affiliation wicri:level="1"><country xml:lang="fr">Taïwan</country><wicri:regionArea>Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan; Taiwan Biobank, Taipei</wicri:regionArea><wicri:noRegion>Taipei</wicri:noRegion></affiliation></author><author><name sortKey="Yu, Jyh Herng" sort="Yu, Jyh Herng" uniqKey="Yu J" first="Jyh-Cherng" last="Yu">Jyh-Cherng Yu</name><affiliation wicri:level="1"><country xml:lang="fr">Taïwan</country><wicri:regionArea>Department of Surgery, Tri‐Service General Hospital, Taipei</wicri:regionArea><wicri:noRegion>Taipei</wicri:noRegion></affiliation></author><author><name sortKey="Wu, Pei I" sort="Wu, Pei I" uniqKey="Wu P" first="Pei-Ei" last="Wu">Pei-Ei Wu</name><affiliation wicri:level="1"><country xml:lang="fr">Taïwan</country><wicri:regionArea>Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan; Taiwan Biobank, Taipei</wicri:regionArea><wicri:noRegion>Taipei</wicri:noRegion></affiliation></author><author><name sortKey="Hou, Ming Eng" sort="Hou, Ming Eng" uniqKey="Hou M" first="Ming-Feng" last="Hou">Ming-Feng Hou</name><affiliation wicri:level="1"><country xml:lang="fr">Taïwan</country><wicri:regionArea>Cancer Center and Department of Surgery, Kaohsiung Medical University Chung‐Ho Memorial Hospital, Kaohsiung</wicri:regionArea><wicri:noRegion>Kaohsiung</wicri:noRegion></affiliation></author><author><name sortKey="Andrulis, Irene L" sort="Andrulis, Irene L" uniqKey="Andrulis I" first="Irene L." last="Andrulis">Irene L. Andrulis</name><affiliation wicri:level="4"><country xml:lang="fr">Canada</country><wicri:regionArea>Ontario Cancer Genetics Network, Cancer Care Ontario; Fred A. Litwin Center for Cancer Genetics, Samuel Lunenfeld Research Institute, Mount Sinai Hospital; Department of Molecular Genetics, University of Toronto, Toronto, Ontario</wicri:regionArea><orgName type="university">Université de Toronto</orgName><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Selander, Teresa" sort="Selander, Teresa" uniqKey="Selander T" first="Teresa" last="Selander">Teresa Selander</name><affiliation wicri:level="1"><country xml:lang="fr">Canada</country><wicri:regionArea>Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Ontario</wicri:regionArea><wicri:noRegion>Ontario</wicri:noRegion></affiliation></author><author><name sortKey="Glendon, Gord" sort="Glendon, Gord" uniqKey="Glendon G" first="Gord" last="Glendon">Gord Glendon</name><affiliation wicri:level="1"><country xml:lang="fr">Canada</country><wicri:regionArea>Ontario Cancer Genetics Network, Cancer Care Ontario, Toronto, Ontario</wicri:regionArea><wicri:noRegion>Ontario</wicri:noRegion></affiliation></author><author><name sortKey="Mulligan, Anna Marie" sort="Mulligan, Anna Marie" uniqKey="Mulligan A" first="Anna Marie" last="Mulligan">Anna Marie Mulligan</name><affiliation wicri:level="4"><country xml:lang="fr">Canada</country><wicri:regionArea>Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON</wicri:regionArea><orgName type="university">Université de Toronto</orgName><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Anton Ulver, Hoda" sort="Anton Ulver, Hoda" uniqKey="Anton Ulver H" first="Hoda" last="Anton-Culver">Hoda Anton-Culver</name><affiliation wicri:level="2"><country>États-Unis</country><placeName><region type="state">Californie</region></placeName><wicri:cityArea>Department of Epidemiology, University of California Irvine, Irvine</wicri:cityArea></affiliation></author><author><name sortKey="Ziogas, Argyrios" sort="Ziogas, Argyrios" uniqKey="Ziogas A" first="Argyrios" last="Ziogas">Argyrios Ziogas</name><affiliation wicri:level="2"><country>États-Unis</country><placeName><region type="state">Californie</region></placeName><wicri:cityArea>Department of Epidemiology, University of California Irvine, Irvine</wicri:cityArea></affiliation></author><author><name sortKey="Muir, Kenneth R" sort="Muir, Kenneth R" uniqKey="Muir K" first="Kenneth R." last="Muir">Kenneth R. Muir</name><affiliation wicri:level="1"><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Health Sciences Research Institute, Warwick Medical School, Warwick University, Coventry</wicri:regionArea><wicri:noRegion>Coventry</wicri:noRegion></affiliation></author><author><name sortKey="Lophatananon, Artitaya" sort="Lophatananon, Artitaya" uniqKey="Lophatananon A" first="Artitaya" last="Lophatananon">Artitaya Lophatananon</name><affiliation wicri:level="1"><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Health Sciences Research Institute, Warwick Medical School, Warwick University, Coventry</wicri:regionArea><wicri:noRegion>Coventry</wicri:noRegion></affiliation></author><author><name sortKey="Rattanamongkongul, Suthee" sort="Rattanamongkongul, Suthee" uniqKey="Rattanamongkongul S" first="Suthee" last="Rattanamongkongul">Suthee Rattanamongkongul</name><affiliation wicri:level="1"><country xml:lang="fr">Thaïlande</country><wicri:regionArea>Department of Preventive Medicine, Srinakhrainwirot University, Ongkharak, Nakhon Nayok</wicri:regionArea><wicri:noRegion>Nakhon Nayok</wicri:noRegion></affiliation></author><author><name sortKey="Puttawibul, Puttisak" sort="Puttawibul, Puttisak" uniqKey="Puttawibul P" first="Puttisak" last="Puttawibul">Puttisak Puttawibul</name><affiliation wicri:level="1"><country xml:lang="fr">Thaïlande</country><wicri:regionArea>Department of Surgery, Medical School, Prince Songkla University, Songkla</wicri:regionArea><wicri:noRegion>Songkla</wicri:noRegion></affiliation></author><author><name sortKey="Jones, Michael" sort="Jones, Michael" uniqKey="Jones M" first="Michael" last="Jones">Michael Jones</name><affiliation wicri:level="1"><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Section of Epidemiology, The Institute of Cancer Research, Sutton, Surrey</wicri:regionArea><wicri:noRegion>Surrey</wicri:noRegion></affiliation></author><author><name sortKey="Orr, Nicholas" sort="Orr, Nicholas" uniqKey="Orr N" first="Nicholas" last="Orr">Nicholas Orr</name><affiliation wicri:level="3"><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Breakthrough Breast Cancer Research Centre, Chester Beatty Laboratories, The Institute of Cancer Research, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Ashworth, Alan" sort="Ashworth, Alan" uniqKey="Ashworth A" first="Alan" last="Ashworth">Alan Ashworth</name><affiliation wicri:level="3"><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Breakthrough Breast Cancer Research Centre, Chester Beatty Laboratories, The Institute of Cancer Research, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Swerdlow, Anthony" sort="Swerdlow, Anthony" uniqKey="Swerdlow A" first="Anthony" last="Swerdlow">Anthony Swerdlow</name><affiliation wicri:level="1"><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Section of Epidemiology, The Institute of Cancer Research, Sutton, Surrey</wicri:regionArea><wicri:noRegion>Surrey</wicri:noRegion></affiliation></author><author><name sortKey="Severi, Gianluca" sort="Severi, Gianluca" uniqKey="Severi G" first="Gianluca" last="Severi">Gianluca Severi</name><affiliation wicri:level="3"><country xml:lang="fr">Australie</country><wicri:regionArea>Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne</wicri:regionArea><placeName><settlement type="city">Melbourne</settlement><region type="état">Victoria (État)</region></placeName></affiliation></author><author><name sortKey="Baglietto, Laura" sort="Baglietto, Laura" uniqKey="Baglietto L" first="Laura" last="Baglietto">Laura Baglietto</name><affiliation wicri:level="3"><country xml:lang="fr">Australie</country><wicri:regionArea>Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne</wicri:regionArea><placeName><settlement type="city">Melbourne</settlement><region type="état">Victoria (État)</region></placeName></affiliation></author><author><name sortKey="Giles, Graham" sort="Giles, Graham" uniqKey="Giles G" first="Graham" last="Giles">Graham Giles</name><affiliation wicri:level="4"><country xml:lang="fr">Australie</country><wicri:regionArea>Centre for Molecular, Environmental, Genetic and Analytic Epidemiology, The University of Melbourne, Melbourne</wicri:regionArea><placeName><settlement type="city">Melbourne</settlement><region type="état">Victoria (État)</region><settlement type="city">Melbourne</settlement></placeName><orgName type="university">Université de Melbourne</orgName></affiliation><affiliation wicri:level="3"><country xml:lang="fr">Australie</country><wicri:regionArea>Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne</wicri:regionArea><placeName><settlement type="city">Melbourne</settlement><region type="état">Victoria (État)</region></placeName></affiliation></author><author><name sortKey="Southey, Melissa" sort="Southey, Melissa" uniqKey="Southey M" first="Melissa" last="Southey">Melissa Southey</name><affiliation wicri:level="3"><country xml:lang="fr">Australie</country><wicri:regionArea>Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne</wicri:regionArea><placeName><settlement type="city">Melbourne</settlement><region type="état">Victoria (État)</region></placeName></affiliation></author><author><name sortKey="Marme, Federik" sort="Marme, Federik" uniqKey="Marme F" first="Federik" last="Marmé">Federik Marmé</name><affiliation wicri:level="3"><country xml:lang="fr">Allemagne</country><wicri:regionArea>National Center for Tumor Diseases, University of Heidelberg, Heidelberg</wicri:regionArea><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Karlsruhe</region><settlement type="city">Heidelberg</settlement></placeName></affiliation><affiliation wicri:level="3"><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Obstetrics and Gynecology, University of Heidelberg, Heidelberg</wicri:regionArea><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Karlsruhe</region><settlement type="city">Heidelberg</settlement></placeName></affiliation></author><author><name sortKey="Schneeweiss, Andreas" sort="Schneeweiss, Andreas" uniqKey="Schneeweiss A" first="Andreas" last="Schneeweiss">Andreas Schneeweiss</name><affiliation wicri:level="3"><country xml:lang="fr">Allemagne</country><wicri:regionArea>National Center for Tumor Diseases, University of Heidelberg, Heidelberg</wicri:regionArea><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Karlsruhe</region><settlement type="city">Heidelberg</settlement></placeName></affiliation><affiliation wicri:level="3"><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Obstetrics and Gynecology, University of Heidelberg, Heidelberg</wicri:regionArea><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Karlsruhe</region><settlement type="city">Heidelberg</settlement></placeName></affiliation></author><author><name sortKey="Sohn, Christof" sort="Sohn, Christof" uniqKey="Sohn C" first="Christof" last="Sohn">Christof Sohn</name><affiliation wicri:level="3"><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Obstetrics and Gynecology, University of Heidelberg, Heidelberg</wicri:regionArea><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Karlsruhe</region><settlement type="city">Heidelberg</settlement></placeName></affiliation></author><author><name sortKey="Burwinkel, Barbara" sort="Burwinkel, Barbara" uniqKey="Burwinkel B" first="Barbara" last="Burwinkel">Barbara Burwinkel</name><affiliation wicri:level="3"><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Obstetrics and Gynecology, University of Heidelberg, Heidelberg</wicri:regionArea><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Karlsruhe</region><settlement type="city">Heidelberg</settlement></placeName></affiliation><affiliation wicri:level="3"><country xml:lang="fr">Allemagne</country><wicri:regionArea>Molecular Epidemiology Group, German Cancer Research Center (DKFZ), Heidelberg</wicri:regionArea><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Karlsruhe</region><settlement type="city">Heidelberg</settlement></placeName></affiliation></author><author><name sortKey="Yesilyurt, Betul T" sort="Yesilyurt, Betul T" uniqKey="Yesilyurt B" first="Betul T." last="Yesilyurt">Betul T. Yesilyurt</name><affiliation wicri:level="1"><country xml:lang="fr">Belgique</country><wicri:regionArea>Vesalius Research Center (VRC), VIB, KU Leuven, Leuven</wicri:regionArea><wicri:noRegion>Leuven</wicri:noRegion></affiliation></author><author><name sortKey="Neven, Patrick" sort="Neven, Patrick" uniqKey="Neven P" first="Patrick" last="Neven">Patrick Neven</name><affiliation wicri:level="1"><country xml:lang="fr">Belgique</country><wicri:regionArea>Multidisciplinary Breast Center, University Hospital Gasthuisberg, Leuven</wicri:regionArea><wicri:noRegion>Leuven</wicri:noRegion></affiliation></author><author><name sortKey="Paridaens, Robert" sort="Paridaens, Robert" uniqKey="Paridaens R" first="Robert" last="Paridaens">Robert Paridaens</name><affiliation wicri:level="1"><country xml:lang="fr">Belgique</country><wicri:regionArea>Multidisciplinary Breast Center, University Hospital Gasthuisberg, Leuven</wicri:regionArea><wicri:noRegion>Leuven</wicri:noRegion></affiliation></author><author><name sortKey="Wildiers, Hans" sort="Wildiers, Hans" uniqKey="Wildiers H" first="Hans" last="Wildiers">Hans Wildiers</name><affiliation wicri:level="1"><country xml:lang="fr">Belgique</country><wicri:regionArea>Multidisciplinary Breast Center, University Hospital Gasthuisberg, Leuven</wicri:regionArea><wicri:noRegion>Leuven</wicri:noRegion></affiliation></author><author><name sortKey="Brenner, Hermann" sort="Brenner, Hermann" uniqKey="Brenner H" first="Hermann" last="Brenner">Hermann Brenner</name><affiliation wicri:level="3"><country xml:lang="fr">Allemagne</country><wicri:regionArea>Division of Clinical Epidemiology and Aging Research, German Cancer Research Center, Heidelberg</wicri:regionArea><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Karlsruhe</region><settlement type="city">Heidelberg</settlement></placeName></affiliation></author><author><name sortKey="Muller, Heiko" sort="Muller, Heiko" uniqKey="Muller H" first="Heiko" last="Müller">Heiko Müller</name><affiliation wicri:level="3"><country xml:lang="fr">Allemagne</country><wicri:regionArea>Division of Clinical Epidemiology and Aging Research, German Cancer Research Center, Heidelberg</wicri:regionArea><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Karlsruhe</region><settlement type="city">Heidelberg</settlement></placeName></affiliation></author><author><name sortKey="Arndt, Volker" sort="Arndt, Volker" uniqKey="Arndt V" first="Volker" last="Arndt">Volker Arndt</name><affiliation wicri:level="3"><country xml:lang="fr">Allemagne</country><wicri:regionArea>Division of Clinical Epidemiology and Aging Research, German Cancer Research Center, Heidelberg</wicri:regionArea><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Karlsruhe</region><settlement type="city">Heidelberg</settlement></placeName></affiliation></author><author><name sortKey="Stegmaier, Christa" sort="Stegmaier, Christa" uniqKey="Stegmaier C" first="Christa" last="Stegmaier">Christa Stegmaier</name><affiliation wicri:level="3"><country xml:lang="fr">Allemagne</country><wicri:regionArea>Saarland Cancer Registry, Saarbrücken</wicri:regionArea><placeName><region type="land" nuts="2">Sarre (Land)</region><settlement type="city">Sarrebruck</settlement></placeName></affiliation></author><author><name sortKey="Meindl, Alfons" sort="Meindl, Alfons" uniqKey="Meindl A" first="Alfons" last="Meindl">Alfons Meindl</name><affiliation wicri:level="4"><country xml:lang="fr">Allemagne</country><wicri:regionArea>Division of Gynaecology and Obstetrics, Technical University of Munich, Munich</wicri:regionArea><placeName><region type="land" nuts="1">Bavière</region><region type="district" nuts="2">District de Haute-Bavière</region><settlement type="city">Munich</settlement><settlement type="city">Munich</settlement></placeName><orgName type="university">Université Louis-et-Maximilien de Munich</orgName></affiliation></author><author><name sortKey="Schott, Sarah" sort="Schott, Sarah" uniqKey="Schott S" first="Sarah" last="Schott">Sarah Schott</name><affiliation wicri:level="3"><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Obstetrics and Gynecology, University of Heidelberg, Heidelberg</wicri:regionArea><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Karlsruhe</region><settlement type="city">Heidelberg</settlement></placeName></affiliation></author><author><name sortKey="Bartram, Claus R" sort="Bartram, Claus R" uniqKey="Bartram C" first="Claus R." last="Bartram">Claus R. Bartram</name><affiliation wicri:level="3"><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Human Genetics, University of Heidelberg, Heidelberg</wicri:regionArea><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Karlsruhe</region><settlement type="city">Heidelberg</settlement></placeName></affiliation></author><author><name sortKey="Schmutzler, Rita K" sort="Schmutzler, Rita K" uniqKey="Schmutzler R" first="Rita K." last="Schmutzler">Rita K. Schmutzler</name><affiliation wicri:level="1"><country xml:lang="fr">Allemagne</country><wicri:regionArea>Division of Molecular Gyneco‐Oncology, Department of Gynaecology and Obstetrics, Center of Molecular Medicine Cologne (CMMC), University Hospital of Cologne, Cologne</wicri:regionArea><wicri:noRegion>Cologne</wicri:noRegion><wicri:noRegion>Cologne</wicri:noRegion></affiliation></author><author><name sortKey="Cox, Angela" sort="Cox, Angela" uniqKey="Cox A" first="Angela" last="Cox">Angela Cox</name><affiliation wicri:level="1"><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Institute for Cancer Studies, Department of Oncology, University of Sheffield</wicri:regionArea><wicri:noRegion>University of Sheffield</wicri:noRegion></affiliation></author><author><name sortKey="Brock, Ian W" sort="Brock, Ian W" uniqKey="Brock I" first="Ian W." last="Brock">Ian W. Brock</name><affiliation wicri:level="1"><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Institute for Cancer Studies, Department of Oncology, University of Sheffield</wicri:regionArea><wicri:noRegion>University of Sheffield</wicri:noRegion></affiliation></author><author><name sortKey="Elliott, Graeme" sort="Elliott, Graeme" uniqKey="Elliott G" first="Graeme" last="Elliott">Graeme Elliott</name><affiliation wicri:level="1"><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Institute for Cancer Studies, Department of Oncology, University of Sheffield</wicri:regionArea><wicri:noRegion>University of Sheffield</wicri:noRegion></affiliation></author><author><name sortKey="Cross, Simon S" sort="Cross, Simon S" uniqKey="Cross S" first="Simon S." last="Cross">Simon S. Cross</name><affiliation wicri:level="1"><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Academic Unit of Pathology, Department of Neuroscience, University of Sheffield</wicri:regionArea><wicri:noRegion>University of Sheffield</wicri:noRegion></affiliation></author><author><name sortKey="Fasching, Peter A" sort="Fasching, Peter A" uniqKey="Fasching P" first="Peter A." last="Fasching">Peter A. Fasching</name><affiliation wicri:level="2"><country>États-Unis</country><placeName><region type="state">Californie</region></placeName><wicri:cityArea>University Breast Center, Department of Gynecology and Obstetrics, University Hospital Erlangen, Erlangen, Germany; David Geffen School of Medicine, Department of Medicine Division of Hematology and Oncology, University of California at Los Angeles</wicri:cityArea></affiliation></author><author><name sortKey="Schulz Endtland, Ruediger" sort="Schulz Endtland, Ruediger" uniqKey="Schulz Endtland R" first="Ruediger" last="Schulz-Wendtland">Ruediger Schulz-Wendtland</name><affiliation wicri:level="3"><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Diagnostic Radiology, University Hospital Erlangen, Erlangen</wicri:regionArea><placeName><settlement type="city">Erlangen</settlement><region type="land" nuts="1">Bavière</region><region type="district" nuts="2">District de Moyenne-Franconie</region></placeName></affiliation></author><author><name sortKey="Ekici, Arif B" sort="Ekici, Arif B" uniqKey="Ekici A" first="Arif B." last="Ekici">Arif B. Ekici</name><affiliation wicri:level="3"><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Human Genetics, Friedrich Alexander University Erlangen‐Nuremberg, Erlangen</wicri:regionArea><placeName><settlement type="city">Erlangen</settlement><region type="land" nuts="1">Bavière</region><region type="district" nuts="2">District de Moyenne-Franconie</region></placeName></affiliation></author><author><name sortKey="Beckmann, Matthias W" sort="Beckmann, Matthias W" uniqKey="Beckmann M" first="Matthias W." last="Beckmann">Matthias W. Beckmann</name><affiliation wicri:level="3"><country xml:lang="fr">Allemagne</country><wicri:regionArea>University Breast Center, Department of Gynecology and Obstetrics, University Hospital Erlangen, Erlangen</wicri:regionArea><placeName><settlement type="city">Erlangen</settlement><region type="land" nuts="1">Bavière</region><region type="district" nuts="2">District de Moyenne-Franconie</region></placeName></affiliation></author><author><name sortKey="Fletcher, Olivia" sort="Fletcher, Olivia" uniqKey="Fletcher O" first="Olivia" last="Fletcher">Olivia Fletcher</name><affiliation wicri:level="3"><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Breakthrough Breast Cancer Research Centre, The Institute of Cancer Research, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Johnson, Nichola" sort="Johnson, Nichola" uniqKey="Johnson N" first="Nichola" last="Johnson">Nichola Johnson</name><affiliation wicri:level="3"><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Breakthrough Breast Cancer Research Centre, The Institute of Cancer Research, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Silva, Isabel Dos Santos" sort="Silva, Isabel Dos Santos" uniqKey="Silva I" first="Isabel Dos Santos" last="Silva">Isabel Dos Santos Silva</name><affiliation wicri:level="3"><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>London School of Hygiene and Tropical Medicine, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Peto, Julian" sort="Peto, Julian" uniqKey="Peto J" first="Julian" last="Peto">Julian Peto</name><affiliation wicri:level="3"><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>London School of Hygiene and Tropical Medicine, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Nevanlinna, Heli" sort="Nevanlinna, Heli" uniqKey="Nevanlinna H" first="Heli" last="Nevanlinna">Heli Nevanlinna</name><affiliation wicri:level="1"><country xml:lang="fr">Finlande</country><wicri:regionArea>Department of Obstetrics and Gynecology, Helsinki University Central Hospital, Biomedicum Helsinki, Helsinki</wicri:regionArea><wicri:noRegion>Helsinki</wicri:noRegion></affiliation></author><author><name sortKey="Muranen, Taru A" sort="Muranen, Taru A" uniqKey="Muranen T" first="Taru A." last="Muranen">Taru A. Muranen</name><affiliation wicri:level="1"><country xml:lang="fr">Finlande</country><wicri:regionArea>Department of Obstetrics and Gynecology, Helsinki University Central Hospital, Biomedicum Helsinki, Helsinki</wicri:regionArea><wicri:noRegion>Helsinki</wicri:noRegion></affiliation></author><author><name sortKey="Aittom Ki, Kristiina" sort="Aittom Ki, Kristiina" uniqKey="Aittom Ki K" first="Kristiina" last="Aittom Ki">Kristiina Aittom Ki</name><affiliation wicri:level="1"><country xml:lang="fr">Finlande</country><wicri:regionArea>Department of Clinical Genetics, Helsinki University Central Hospital, Helsinki</wicri:regionArea><wicri:noRegion>Helsinki</wicri:noRegion></affiliation></author><author><name sortKey="Blomqvist, Carl" sort="Blomqvist, Carl" uniqKey="Blomqvist C" first="Carl" last="Blomqvist">Carl Blomqvist</name><affiliation wicri:level="1"><country xml:lang="fr">Finlande</country><wicri:regionArea>Department of Oncology, Helsinki University Central Hospital, Helsinki</wicri:regionArea><wicri:noRegion>Helsinki</wicri:noRegion></affiliation></author><author><name sortKey="Dork, Thilo" sort="Dork, Thilo" uniqKey="Dork T" first="Thilo" last="Dörk">Thilo Dörk</name><affiliation wicri:level="3"><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Obstetrics and Gynaecology, Hannover Medical School, Hannover</wicri:regionArea><placeName><region type="land" nuts="2">Basse-Saxe</region><settlement type="city">Hanovre</settlement></placeName></affiliation></author><author><name sortKey="Schurmann, Peter" sort="Schurmann, Peter" uniqKey="Schurmann P" first="Peter" last="Schürmann">Peter Schürmann</name><affiliation wicri:level="3"><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Obstetrics and Gynaecology, Hannover Medical School, Hannover</wicri:regionArea><placeName><region type="land" nuts="2">Basse-Saxe</region><settlement type="city">Hanovre</settlement></placeName></affiliation></author><author><name sortKey="Bremer, Michael" sort="Bremer, Michael" uniqKey="Bremer M" first="Michael" last="Bremer">Michael Bremer</name><affiliation wicri:level="3"><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Radiation Oncology, Hannover Medical School, Hannover</wicri:regionArea><placeName><region type="land" nuts="2">Basse-Saxe</region><settlement type="city">Hanovre</settlement></placeName></affiliation></author><author><name sortKey="Hillemanns, Peter" sort="Hillemanns, Peter" uniqKey="Hillemanns P" first="Peter" last="Hillemanns">Peter Hillemanns</name><affiliation wicri:level="3"><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Obstetrics and Gynaecology, Hannover Medical School, Hannover</wicri:regionArea><placeName><region type="land" nuts="2">Basse-Saxe</region><settlement type="city">Hanovre</settlement></placeName></affiliation></author><author><name sortKey="Bogdanova, Natalia V" sort="Bogdanova, Natalia V" uniqKey="Bogdanova N" first="Natalia V." last="Bogdanova">Natalia V. Bogdanova</name><affiliation wicri:level="3"><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Obstetrics and Gynaecology, Hannover Medical School, Hannover</wicri:regionArea><placeName><region type="land" nuts="2">Basse-Saxe</region><settlement type="city">Hanovre</settlement></placeName></affiliation><affiliation wicri:level="3"><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Radiation Oncology, Hannover Medical School, Hannover</wicri:regionArea><placeName><region type="land" nuts="2">Basse-Saxe</region><settlement type="city">Hanovre</settlement></placeName></affiliation></author><author><name sortKey="Antonenkova, Natalia N" sort="Antonenkova, Natalia N" uniqKey="Antonenkova N" first="Natalia N." last="Antonenkova">Natalia N. Antonenkova</name><affiliation wicri:level="1"><country xml:lang="fr">Biélorussie</country><wicri:regionArea>N.N. Alexandrov Research Institute of Oncology and Medical Radiology, Minsk</wicri:regionArea><wicri:noRegion>Minsk</wicri:noRegion></affiliation></author><author><name sortKey="Rogov, Yuri I" sort="Rogov, Yuri I" uniqKey="Rogov Y" first="Yuri I." last="Rogov">Yuri I. Rogov</name><affiliation wicri:level="1"><country xml:lang="fr">Biélorussie</country><wicri:regionArea>N.N. Alexandrov Research Institute of Oncology and Medical Radiology, Minsk</wicri:regionArea><wicri:noRegion>Minsk</wicri:noRegion></affiliation></author><author><name sortKey="Karstens, Johann H" sort="Karstens, Johann H" uniqKey="Karstens J" first="Johann H." last="Karstens">Johann H. Karstens</name><affiliation wicri:level="3"><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Obstetrics and Gynaecology, Hannover Medical School, Hannover</wicri:regionArea><placeName><region type="land" nuts="2">Basse-Saxe</region><settlement type="city">Hanovre</settlement></placeName></affiliation></author><author><name sortKey="Khusnutdinova, Elza" sort="Khusnutdinova, Elza" uniqKey="Khusnutdinova E" first="Elza" last="Khusnutdinova">Elza Khusnutdinova</name><affiliation wicri:level="1"><country xml:lang="fr">Russie</country><wicri:regionArea>Institute of Biochemistry and Genetics, Ufa Scientific Center of Russian Academy of Sciences, Ufa</wicri:regionArea><wicri:noRegion>Ufa</wicri:noRegion></affiliation></author><author><name sortKey="Bermisheva, Marina" sort="Bermisheva, Marina" uniqKey="Bermisheva M" first="Marina" last="Bermisheva">Marina Bermisheva</name><affiliation wicri:level="1"><country xml:lang="fr">Russie</country><wicri:regionArea>Institute of Biochemistry and Genetics, Ufa Scientific Center of Russian Academy of Sciences, Ufa</wicri:regionArea><wicri:noRegion>Ufa</wicri:noRegion></affiliation></author><author><name sortKey="Prokofieva, Darya" sort="Prokofieva, Darya" uniqKey="Prokofieva D" first="Darya" last="Prokofieva">Darya Prokofieva</name><affiliation wicri:level="1"><country xml:lang="fr">Russie</country><wicri:regionArea>Institute of Biochemistry and Genetics, Ufa Scientific Center of Russian Academy of Sciences, Ufa</wicri:regionArea><wicri:noRegion>Ufa</wicri:noRegion></affiliation></author><author><name sortKey="Gancev, Shamil" sort="Gancev, Shamil" uniqKey="Gancev S" first="Shamil" last="Gancev">Shamil Gancev</name><affiliation wicri:level="1"><country xml:lang="fr">Russie</country><wicri:regionArea>Bashkirian Medical University, Ufa</wicri:regionArea><wicri:noRegion>Ufa</wicri:noRegion></affiliation></author><author><name sortKey="Jakubowska, Anna" sort="Jakubowska, Anna" uniqKey="Jakubowska A" first="Anna" last="Jakubowska">Anna Jakubowska</name><affiliation wicri:level="1"><country xml:lang="fr">Pologne</country><wicri:regionArea>Department of Genetics and Pathology, Pomeranian Medical University, Szczecin</wicri:regionArea><wicri:noRegion>Szczecin</wicri:noRegion></affiliation></author><author><name sortKey="Lubinski, Jan" sort="Lubinski, Jan" uniqKey="Lubinski J" first="Jan" last="Lubinski">Jan Lubinski</name><affiliation wicri:level="1"><country xml:lang="fr">Pologne</country><wicri:regionArea>Department of Genetics and Pathology, Pomeranian Medical University, Szczecin</wicri:regionArea><wicri:noRegion>Szczecin</wicri:noRegion></affiliation></author><author><name sortKey="Jaworska, Katarzyna" sort="Jaworska, Katarzyna" uniqKey="Jaworska K" first="Katarzyna" last="Jaworska">Katarzyna Jaworska</name><affiliation wicri:level="1"><country xml:lang="fr">Pologne</country><wicri:regionArea>Department of Genetics and Pathology, Pomeranian Medical University, Szczecin</wicri:regionArea><wicri:noRegion>Szczecin</wicri:noRegion></affiliation><affiliation wicri:level="1"><country xml:lang="fr">Pologne</country><wicri:regionArea>Postgraduate School of Molecular Medicine, Warsaw Medical University, Warsaw</wicri:regionArea><wicri:noRegion>Warsaw</wicri:noRegion></affiliation></author><author><name sortKey="Durda, Katarzyna" sort="Durda, Katarzyna" uniqKey="Durda K" first="Katarzyna" last="Durda">Katarzyna Durda</name><affiliation wicri:level="1"><country xml:lang="fr">Pologne</country><wicri:regionArea>Department of Genetics and Pathology, Pomeranian Medical University, Szczecin</wicri:regionArea><wicri:noRegion>Szczecin</wicri:noRegion></affiliation></author><author><name sortKey="Nordestgaard, B Rge G" sort="Nordestgaard, B Rge G" uniqKey="Nordestgaard B" first="B Rge G." last="Nordestgaard">B Rge G. Nordestgaard</name><affiliation wicri:level="3"><country xml:lang="fr">Danemark</country><wicri:regionArea>Copenhagen General Population Study and Department of Clinical Biochemistry, Herlev University Hospital, University of Copenhagen, Copenhagen</wicri:regionArea><placeName><settlement type="city">Copenhague</settlement><region type="région" nuts="2">Hovedstaden</region></placeName></affiliation></author><author><name sortKey="Bojesen, Stig E" sort="Bojesen, Stig E" uniqKey="Bojesen S" first="Stig E." last="Bojesen">Stig E. Bojesen</name><affiliation wicri:level="3"><country xml:lang="fr">Danemark</country><wicri:regionArea>Copenhagen General Population Study and Department of Clinical Biochemistry, Herlev University Hospital, University of Copenhagen, Copenhagen</wicri:regionArea><placeName><settlement type="city">Copenhague</settlement><region type="région" nuts="2">Hovedstaden</region></placeName></affiliation></author><author><name sortKey="Lanng, Charlotte" sort="Lanng, Charlotte" uniqKey="Lanng C" first="Charlotte" last="Lanng">Charlotte Lanng</name><affiliation wicri:level="3"><country xml:lang="fr">Danemark</country><wicri:regionArea>Department of Breast Surgery, Herlev University Hospital, University of Copenhagen, Copenhagen</wicri:regionArea><placeName><settlement type="city">Copenhague</settlement><region type="région" nuts="2">Hovedstaden</region></placeName></affiliation></author><author><name sortKey="Mannermaa, Arto" sort="Mannermaa, Arto" uniqKey="Mannermaa A" first="Arto" last="Mannermaa">Arto Mannermaa</name><affiliation wicri:level="1"><country xml:lang="fr">Finlande</country><wicri:regionArea>School of Medicine, Institute of Clinical Medicine, Pathology and Forensic Medicine, University of Eastern Finland; Biocenter Kuopio and Department of Clinical Pathology, Kuopio University Hospital, Kuopio</wicri:regionArea><wicri:noRegion>Kuopio</wicri:noRegion></affiliation></author><author><name sortKey="Kataja, Vesa" sort="Kataja, Vesa" uniqKey="Kataja V" first="Vesa" last="Kataja">Vesa Kataja</name><affiliation wicri:level="1"><country xml:lang="fr">Finlande</country><wicri:regionArea>School of Medicine, Institute of Clinical Medicine, Oncology, University of Eastern Finland; Biocenter Kuopio and Department of Oncology, Kuopio University Hospital, Kuopio</wicri:regionArea><wicri:noRegion>Kuopio</wicri:noRegion></affiliation></author><author><name sortKey="Kosma, Veli Atti" sort="Kosma, Veli Atti" uniqKey="Kosma V" first="Veli-Matti" last="Kosma">Veli-Matti Kosma</name><affiliation wicri:level="1"><country xml:lang="fr">Finlande</country><wicri:regionArea>School of Medicine, Institute of Clinical Medicine, Pathology and Forensic Medicine, University of Eastern Finland; Biocenter Kuopio and Department of Clinical Pathology, Kuopio University Hospital, Kuopio</wicri:regionArea><wicri:noRegion>Kuopio</wicri:noRegion></affiliation></author><author><name sortKey="Hartikainen, Jaana M" sort="Hartikainen, Jaana M" uniqKey="Hartikainen J" first="Jaana M." last="Hartikainen">Jaana M. Hartikainen</name><affiliation wicri:level="1"><country xml:lang="fr">Finlande</country><wicri:regionArea>School of Medicine, Institute of Clinical Medicine, Pathology and Forensic Medicine, University of Eastern Finland; Biocenter Kuopio and Department of Clinical Pathology, Kuopio University Hospital, Kuopio</wicri:regionArea><wicri:noRegion>Kuopio</wicri:noRegion></affiliation></author><author><name sortKey="Radice, Paolo" sort="Radice, Paolo" uniqKey="Radice P" first="Paolo" last="Radice">Paolo Radice</name><affiliation wicri:level="3"><country xml:lang="fr">Italie</country><wicri:regionArea>Unit of Molecular Bases of Genetic Risk and Genetic Testing, Department of Preventive and Predicted Medicine, Fondazione IRCCS Istituto Nazionale Tumori (INT); IFOM, Fondazione Istituto FIRC di Oncologia Molecolare, Milan</wicri:regionArea><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation></author><author><name sortKey="Peterlongo, Paolo" sort="Peterlongo, Paolo" uniqKey="Peterlongo P" first="Paolo" last="Peterlongo">Paolo Peterlongo</name><affiliation wicri:level="3"><country xml:lang="fr">Italie</country><wicri:regionArea>Unit of Molecular Bases of Genetic Risk and Genetic Testing, Department of Preventive and Predicted Medicine, Fondazione IRCCS Istituto Nazionale Tumori (INT); IFOM, Fondazione Istituto FIRC di Oncologia Molecolare, Milan</wicri:regionArea><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation></author><author><name sortKey="Manoukian, Siranoush" sort="Manoukian, Siranoush" uniqKey="Manoukian S" first="Siranoush" last="Manoukian">Siranoush Manoukian</name><affiliation wicri:level="3"><country xml:lang="fr">Italie</country><wicri:regionArea>Unit of Medical Genetics, Department of Preventive and Predictive Medicine, Fondazione IRCCS Istituto Nazionale Tumori (INT), Milan</wicri:regionArea><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation></author><author><name sortKey="Bernard, Loris" sort="Bernard, Loris" uniqKey="Bernard L" first="Loris" last="Bernard">Loris Bernard</name><affiliation wicri:level="1"><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Experimental Oncology, Istituto Europeo di Oncologia (IEO); Consortium for Genomics Technology (Cogentech) Milan</wicri:regionArea><wicri:noRegion>Istituto Europeo di Oncologia (IEO); Consortium for Genomics Technology (Cogentech) Milan</wicri:noRegion></affiliation></author><author><name sortKey="Couch, Fergus J" sort="Couch, Fergus J" uniqKey="Couch F" first="Fergus J." last="Couch">Fergus J. Couch</name><affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country><placeName><region type="state">Minnesota</region></placeName><wicri:cityArea>Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester</wicri:cityArea></affiliation></author><author><name sortKey="Olson, Janet E" sort="Olson, Janet E" uniqKey="Olson J" first="Janet E." last="Olson">Janet E. Olson</name><affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country><placeName><region type="state">Minnesota</region></placeName><wicri:cityArea>Department of Health Sciences Research, Mayo Clinic, Rochester</wicri:cityArea></affiliation></author><author><name sortKey="Wang, Xianshu" sort="Wang, Xianshu" uniqKey="Wang X" first="Xianshu" last="Wang">Xianshu Wang</name><affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country><placeName><region type="state">Minnesota</region></placeName><wicri:cityArea>Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester</wicri:cityArea></affiliation></author><author><name sortKey="Fredericksen, Zachary" sort="Fredericksen, Zachary" uniqKey="Fredericksen Z" first="Zachary" last="Fredericksen">Zachary Fredericksen</name><affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country><placeName><region type="state">Minnesota</region></placeName><wicri:cityArea>Department of Health Sciences Research, Mayo Clinic, Rochester</wicri:cityArea></affiliation></author><author><name sortKey="Aln S, Grethe Grenaker" sort="Aln S, Grethe Grenaker" uniqKey="Aln S G" first="Grethe Grenaker" last="Aln S">Grethe Grenaker Aln S</name><affiliation wicri:level="3"><country xml:lang="fr">Norvège</country><wicri:regionArea>Department of Genetics, Institute for Cancer Research, Oslo University Hospital, Radiumhospitalet, Oslo</wicri:regionArea><placeName><settlement type="city">Oslo</settlement><region nuts="2">Østlandet</region></placeName></affiliation></author><author><name sortKey="Kristensen, Vessela" sort="Kristensen, Vessela" uniqKey="Kristensen V" first="Vessela" last="Kristensen">Vessela Kristensen</name><affiliation wicri:level="3"><country xml:lang="fr">Norvège</country><wicri:regionArea>Department of Genetics, Institute for Cancer Research, Oslo University Hospital, Radiumhospitalet, Oslo</wicri:regionArea><placeName><settlement type="city">Oslo</settlement><region nuts="2">Østlandet</region></placeName></affiliation><affiliation wicri:level="1"><country xml:lang="fr">Norvège</country><wicri:regionArea>Faculty of Medicine (Faculty Division Ahus), University of Oslo</wicri:regionArea><wicri:noRegion>University of Oslo</wicri:noRegion></affiliation></author><author><name sortKey="B Rresen Ale, Anne Ise" sort="B Rresen Ale, Anne Ise" uniqKey="B Rresen Ale A" first="Anne-Lise" last="B Rresen-Dale">Anne-Lise B Rresen-Dale</name><affiliation wicri:level="3"><country xml:lang="fr">Norvège</country><wicri:regionArea>Department of Genetics, Institute for Cancer Research, Oslo University Hospital, Radiumhospitalet, Oslo</wicri:regionArea><placeName><settlement type="city">Oslo</settlement><region nuts="2">Østlandet</region></placeName></affiliation><affiliation wicri:level="1"><country xml:lang="fr">Norvège</country><wicri:regionArea>Faculty of Medicine (Faculty Division Ahus), University of Oslo</wicri:regionArea><wicri:noRegion>University of Oslo</wicri:noRegion></affiliation></author><author><name sortKey="Devilee, Peter" sort="Devilee, Peter" uniqKey="Devilee P" first="Peter" last="Devilee">Peter Devilee</name><affiliation wicri:level="3"><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Human Genetics, and Department of Pathology, Leiden University Medical Centre, Leiden</wicri:regionArea><placeName><settlement type="city">Leyde</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Tollenaar, Robert A E M" sort="Tollenaar, Robert A E M" uniqKey="Tollenaar R" first="Robert A. E. M." last="Tollenaar">Robert A. E. M. Tollenaar</name><affiliation wicri:level="3"><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Surgery, Leiden University Medical Center, Leiden</wicri:regionArea><placeName><settlement type="city">Leyde</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Seynaeve, Caroline M" sort="Seynaeve, Caroline M" uniqKey="Seynaeve C" first="Caroline M." last="Seynaeve">Caroline M. Seynaeve</name><affiliation wicri:level="3"><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Medical Oncology, Rotterdam Family Cancer Clinic, Erasmus MC‐Daniel den Hoed Cancer Center, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Hooning, Maartje J" sort="Hooning, Maartje J" uniqKey="Hooning M" first="Maartje J." last="Hooning">Maartje J. Hooning</name><affiliation wicri:level="3"><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Medical Oncology, Rotterdam Family Cancer Clinic, Erasmus MC‐Daniel den Hoed Cancer Center, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Garcia Losas, Montserrat" sort="Garcia Losas, Montserrat" uniqKey="Garcia Losas M" first="Montserrat" last="García-Closas">Montserrat García-Closas</name><affiliation wicri:level="3"><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland; Division of Genetics and Epidemiology, Institute of Cancer Research and Breakthrough Breast Cancer Research Centre, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Chanock, Stephen J" sort="Chanock, Stephen J" uniqKey="Chanock S" first="Stephen J." last="Chanock">Stephen J. Chanock</name><affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country><placeName><region type="state">Maryland</region></placeName><wicri:cityArea>Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville</wicri:cityArea></affiliation></author><author><name sortKey="Lissowska, Jolanta" sort="Lissowska, Jolanta" uniqKey="Lissowska J" first="Jolanta" last="Lissowska">Jolanta Lissowska</name><affiliation wicri:level="1"><country xml:lang="fr">Pologne</country><wicri:regionArea>Department of Cancer Epidemiology and Prevention, M. Sklodowska‐Curie Memorial Cancer Center and Institute of Oncology, Warsaw</wicri:regionArea><wicri:noRegion>Warsaw</wicri:noRegion></affiliation></author><author><name sortKey="Sherman, Mark E" sort="Sherman, Mark E" uniqKey="Sherman M" first="Mark E." last="Sherman">Mark E. Sherman</name><affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country><placeName><region type="state">Maryland</region></placeName><wicri:cityArea>Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville</wicri:cityArea></affiliation></author><author><name sortKey="Hall, Per" sort="Hall, Per" uniqKey="Hall P" first="Per" last="Hall">Per Hall</name><affiliation wicri:level="3"><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm</wicri:regionArea><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName></affiliation></author><author><name sortKey="Liu, Jianjun" sort="Liu, Jianjun" uniqKey="Liu J" first="Jianjun" last="Liu">Jianjun Liu</name><affiliation wicri:level="3"><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm</wicri:regionArea><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName></affiliation></author><author><name sortKey="Czene, Kamila" sort="Czene, Kamila" uniqKey="Czene K" first="Kamila" last="Czene">Kamila Czene</name><affiliation wicri:level="3"><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm</wicri:regionArea><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName></affiliation></author><author><name sortKey="Kang, Daehee" sort="Kang, Daehee" uniqKey="Kang D" first="Daehee" last="Kang">Daehee Kang</name><affiliation wicri:level="3"><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>Seoul National University College of Medicine, Seoul</wicri:regionArea><placeName><settlement type="city">Séoul</settlement><region type="capital">Région capitale de Séoul</region></placeName></affiliation></author><author><name sortKey="Yoo, Keun Oung" sort="Yoo, Keun Oung" uniqKey="Yoo K" first="Keun-Young" last="Yoo">Keun-Young Yoo</name><affiliation wicri:level="3"><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>Seoul National University College of Medicine, Seoul</wicri:regionArea><placeName><settlement type="city">Séoul</settlement><region type="capital">Région capitale de Séoul</region></placeName></affiliation></author><author><name sortKey="Noh, Dong Oung" sort="Noh, Dong Oung" uniqKey="Noh D" first="Dong-Young" last="Noh">Dong-Young Noh</name><affiliation wicri:level="3"><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>Seoul National University College of Medicine, Seoul</wicri:regionArea><placeName><settlement type="city">Séoul</settlement><region type="capital">Région capitale de Séoul</region></placeName></affiliation></author><author><name sortKey="Lindblom, Annika" sort="Lindblom, Annika" uniqKey="Lindblom A" first="Annika" last="Lindblom">Annika Lindblom</name><affiliation wicri:level="3"><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm</wicri:regionArea><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName></affiliation></author><author><name sortKey="Margolin, Sara" sort="Margolin, Sara" uniqKey="Margolin S" first="Sara" last="Margolin">Sara Margolin</name><affiliation wicri:level="3"><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Oncology Pathology, Karolinska Institutet, Stockholm</wicri:regionArea><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName></affiliation></author><author><name sortKey="Dunning, Alison M" sort="Dunning, Alison M" uniqKey="Dunning A" first="Alison M." last="Dunning">Alison M. Dunning</name><affiliation wicri:level="4"><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge</wicri:regionArea><orgName type="university">Université de Cambridge</orgName><placeName><settlement type="city">Cambridge</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Angleterre de l'Est</region></placeName></affiliation></author><author><name sortKey="Pharoah, Paul D P" sort="Pharoah, Paul D P" uniqKey="Pharoah P" first="Paul D. P." last="Pharoah">Paul D. P. Pharoah</name><affiliation wicri:level="4"><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge</wicri:regionArea><orgName type="university">Université de Cambridge</orgName><placeName><settlement type="city">Cambridge</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Angleterre de l'Est</region></placeName></affiliation><affiliation wicri:level="4"><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge</wicri:regionArea><orgName type="university">Université de Cambridge</orgName><placeName><settlement type="city">Cambridge</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Angleterre de l'Est</region></placeName></affiliation></author><author><name sortKey="Easton, Douglas F" sort="Easton, Douglas F" uniqKey="Easton D" first="Douglas F." last="Easton">Douglas F. Easton</name><affiliation wicri:level="4"><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge</wicri:regionArea><orgName type="university">Université de Cambridge</orgName><placeName><settlement type="city">Cambridge</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Angleterre de l'Est</region></placeName></affiliation><affiliation wicri:level="4"><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge</wicri:regionArea><orgName type="university">Université de Cambridge</orgName><placeName><settlement type="city">Cambridge</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Angleterre de l'Est</region></placeName></affiliation></author><author><name sortKey="Guenel, Pascal" sort="Guenel, Pascal" uniqKey="Guenel P" first="Pascal" last="Guénel">Pascal Guénel</name><affiliation wicri:level="3"><country xml:lang="fr">France</country><wicri:regionArea>Environmental Epidemiology of Cancer, CESP Centre for Research in Epidemiology and Population Health, U1018, Inserm, F‐94807, Villejuif</wicri:regionArea><placeName><region type="region" nuts="2">Île-de-France</region><settlement type="city">Villejuif</settlement></placeName></affiliation><affiliation wicri:level="1"><country xml:lang="fr">France</country><wicri:regionArea>University Paris‐Sud, UMRS 1018, Villejuif</wicri:regionArea><wicri:noRegion>Villejuif</wicri:noRegion><wicri:noRegion>Villejuif</wicri:noRegion></affiliation></author><author><name sortKey="Brauch, Hiltrud" sort="Brauch, Hiltrud" uniqKey="Brauch H" first="Hiltrud" last="Brauch">Hiltrud Brauch</name><affiliation wicri:level="3"><country xml:lang="fr">Allemagne</country><wicri:regionArea>Dr. Margarete Fischer‐Bosch‐Institute of Clinical Pharmacology, Stuttgart; University Tübingen, Tübingen</wicri:regionArea><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Tübingen</region><settlement type="city">Tübingen</settlement></placeName></affiliation><affiliation wicri:level="1"><country wicri:rule="url">Allemagne</country></affiliation><affiliation wicri:level="3"><country xml:lang="fr">Allemagne</country><wicri:regionArea>Correspondence address: Dr. Margarete Fischer‐Bosch‐Institute of Clinical Pharmacology, Auerbachstr. 112, 70376 Stuttgart</wicri:regionArea><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Stuttgart</region><settlement type="city">Stuttgart</settlement></placeName></affiliation></author></analytic><monogr></monogr><series><title level="j" type="main">Human Mutation</title><title level="j" type="alt">HUMAN MUTATION</title><idno type="ISSN">1059-7794</idno><idno type="eISSN">1098-1004</idno><imprint><biblScope unit="vol">33</biblScope><biblScope unit="issue">7</biblScope><biblScope unit="page" from="1123">1123</biblScope><biblScope unit="page" to="1132">1132</biblScope><biblScope unit="page-count">10</biblScope><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><pubPlace>Hoboken</pubPlace><date type="published" when="2012-07">2012-07</date></imprint><idno type="ISSN">1059-7794</idno></series></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">1059-7794</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Abcfs</term><term>Academia sinica</term><term>Accident insurance</term><term>Acute lymphoblastic leukaemia</term><term>Allele</term><term>Asian descent</term><term>Asian women</term><term>Association study</term><term>Bcac</term><term>Biocenter kuopio</term><term>Biomedical research centre</term><term>Biomedical sciences</term><term>Brca1</term><term>Brca1 mutations</term><term>Breakthrough breast cancer</term><term>Breakthrough breast cancer research centre</term><term>Breast</term><term>Breast cancer</term><term>Breast cancer association consortium</term><term>Breast cancer cases</term><term>Breast cancer family registry</term><term>Breast cancer patients</term><term>Breast cancer risk</term><term>Breast cancer susceptibility loci</term><term>Bsuch study</term><term>Cancer</term><term>Cancer care ontario</term><term>Cancer council victoria</term><term>Cancer epidemiology</term><term>Cancer foundation</term><term>Cancer genetics</term><term>Cancer institute</term><term>Cancer prevention institute</term><term>Cancer research</term><term>Cancer research centre</term><term>Cancer studies</term><term>Cecile study</term><term>Cell cycle control</term><term>Centre</term><term>Clin</term><term>Clin cancer</term><term>Clinical genetics</term><term>Clinical medicine</term><term>Clinical pharmacology</term><term>College london</term><term>Common variants</term><term>Consortium</term><term>Coriell institute</term><term>Coronary artery disease</term><term>Cyclin</term><term>Deutsche krebshilfe</term><term>Deutsches krebsforschungszentrum</term><term>Dkfz</term><term>Ductal</term><term>Dutch cancer society</term><term>Eastern finland</term><term>Epidemiol</term><term>Epidemiology</term><term>Erlangen</term><term>Estrogen</term><term>Estrogen breast cancer</term><term>Estrogen receptor</term><term>European descent</term><term>European women</term><term>Evangelische kliniken bonn ggmbh</term><term>Familial breast cancer risk</term><term>Family history</term><term>Federal ministry</term><term>Finland</term><term>Fondazione irccs istituto nazionale tumori</term><term>Forest plots</term><term>Foundation trust</term><term>Gene expression</term><term>General population</term><term>Genet</term><term>Genetic variants</term><term>Genetics</term><term>German cancer research center</term><term>Gwas</term><term>Heidelberg</term><term>Helmholtz society</term><term>Helsinki</term><term>Helsinki university</term><term>Herlev university hospital</term><term>Heterogeneity</term><term>Heterozygous</term><term>Hiltrud brauch</term><term>Histology</term><term>Histology ductal</term><term>Histopathological subtype</term><term>Homozygous effect</term><term>Horizontal lines</term><term>Hormone receptor status</term><term>Human cancer genetics programme</term><term>Human genetics</term><term>Human mutation</term><term>Inst</term><term>Internal medicine</term><term>Johanniter krankenhaus</term><term>Kuopio</term><term>Kuopio university hospital</term><term>Laboratory medicine</term><term>Leiden university</term><term>Lobular</term><term>Locus</term><term>Mammographic density</term><term>Many others</term><term>Mayo clinic</term><term>Medical research</term><term>Medical research council</term><term>Melbourne</term><term>Minor allele frequencies</term><term>Molecular epidemiology group</term><term>Molecular genetics</term><term>Molecular medicine</term><term>Mutation</term><term>National cancer institute</term><term>National health</term><term>Natl</term><term>Natl cancer inst</term><term>Nhmrc</term><term>Obstetrics</term><term>Occupational medicine</term><term>Odds ratio</term><term>Odds ratios</term><term>Ofbcr</term><term>Oncogenic driver</term><term>Oncology</term><term>Ontario</term><term>Ontario cancer genetics network</term><term>Other tumors</term><term>Oulu</term><term>Oulu university hospital</term><term>Ovarian cancer</term><term>Pancreatic cancer</term><term>Polymorphism</term><term>Postgraduate school</term><term>Receptor</term><term>Repair genes</term><term>Research centre</term><term>Sample sizes</term><term>Samuel lunenfeld research institute</term><term>Sigrid juselius foundation</term><term>Sinai hospital</term><term>Single nucleotide polymorphism</term><term>Snp</term><term>Study abcfs</term><term>Study participants</term><term>Subgroup analyses</term><term>Susceptibility</term><term>Tumor characteristics</term><term>Tumor subtype</term><term>Tumor subtypes</term><term>Turnbull</term><term>Ucibcs</term><term>University breast center</term><term>University hospital</term><term>University hospital erlangen</term><term>University tubingen</term><term>Unselected breast cancer patients</term><term>Variant</term><term>Victorian breast cancer research consortium group leader</term><term>Western australia</term><term>Wiley periodicals</term></keywords><keywords scheme="Teeft" xml:lang="en"><term>Abcfs</term><term>Academia sinica</term><term>Accident insurance</term><term>Acute lymphoblastic leukaemia</term><term>Allele</term><term>Asian descent</term><term>Asian women</term><term>Association study</term><term>Bcac</term><term>Biocenter kuopio</term><term>Biomedical research centre</term><term>Biomedical sciences</term><term>Brca1</term><term>Brca1 mutations</term><term>Breakthrough breast cancer</term><term>Breakthrough breast cancer research centre</term><term>Breast</term><term>Breast cancer</term><term>Breast cancer association consortium</term><term>Breast cancer cases</term><term>Breast cancer family registry</term><term>Breast cancer patients</term><term>Breast cancer risk</term><term>Breast cancer susceptibility loci</term><term>Bsuch study</term><term>Cancer</term><term>Cancer care ontario</term><term>Cancer council victoria</term><term>Cancer epidemiology</term><term>Cancer foundation</term><term>Cancer genetics</term><term>Cancer institute</term><term>Cancer prevention institute</term><term>Cancer research</term><term>Cancer research centre</term><term>Cancer studies</term><term>Cecile study</term><term>Cell cycle control</term><term>Centre</term><term>Clin</term><term>Clin cancer</term><term>Clinical genetics</term><term>Clinical medicine</term><term>Clinical pharmacology</term><term>College london</term><term>Common variants</term><term>Consortium</term><term>Coriell institute</term><term>Coronary artery disease</term><term>Cyclin</term><term>Deutsche krebshilfe</term><term>Deutsches krebsforschungszentrum</term><term>Dkfz</term><term>Ductal</term><term>Dutch cancer society</term><term>Eastern finland</term><term>Epidemiol</term><term>Epidemiology</term><term>Erlangen</term><term>Estrogen</term><term>Estrogen breast cancer</term><term>Estrogen receptor</term><term>European descent</term><term>European women</term><term>Evangelische kliniken bonn ggmbh</term><term>Familial breast cancer risk</term><term>Family history</term><term>Federal ministry</term><term>Finland</term><term>Fondazione irccs istituto nazionale tumori</term><term>Forest plots</term><term>Foundation trust</term><term>Gene expression</term><term>General population</term><term>Genet</term><term>Genetic variants</term><term>Genetics</term><term>German cancer research center</term><term>Gwas</term><term>Heidelberg</term><term>Helmholtz society</term><term>Helsinki</term><term>Helsinki university</term><term>Herlev university hospital</term><term>Heterogeneity</term><term>Heterozygous</term><term>Hiltrud brauch</term><term>Histology</term><term>Histology ductal</term><term>Histopathological subtype</term><term>Homozygous effect</term><term>Horizontal lines</term><term>Hormone receptor status</term><term>Human cancer genetics programme</term><term>Human genetics</term><term>Human mutation</term><term>Inst</term><term>Internal medicine</term><term>Johanniter krankenhaus</term><term>Kuopio</term><term>Kuopio university hospital</term><term>Laboratory medicine</term><term>Leiden university</term><term>Lobular</term><term>Locus</term><term>Mammographic density</term><term>Many others</term><term>Mayo clinic</term><term>Medical research</term><term>Medical research council</term><term>Melbourne</term><term>Minor allele frequencies</term><term>Molecular epidemiology group</term><term>Molecular genetics</term><term>Molecular medicine</term><term>Mutation</term><term>National cancer institute</term><term>National health</term><term>Natl</term><term>Natl cancer inst</term><term>Nhmrc</term><term>Obstetrics</term><term>Occupational medicine</term><term>Odds ratio</term><term>Odds ratios</term><term>Ofbcr</term><term>Oncogenic driver</term><term>Oncology</term><term>Ontario</term><term>Ontario cancer genetics network</term><term>Other tumors</term><term>Oulu</term><term>Oulu university hospital</term><term>Ovarian cancer</term><term>Pancreatic cancer</term><term>Polymorphism</term><term>Postgraduate school</term><term>Receptor</term><term>Repair genes</term><term>Research centre</term><term>Sample sizes</term><term>Samuel lunenfeld research institute</term><term>Sigrid juselius foundation</term><term>Sinai hospital</term><term>Single nucleotide polymorphism</term><term>Snp</term><term>Study abcfs</term><term>Study participants</term><term>Subgroup analyses</term><term>Susceptibility</term><term>Tumor characteristics</term><term>Tumor subtype</term><term>Tumor subtypes</term><term>Turnbull</term><term>Ucibcs</term><term>University breast center</term><term>University hospital</term><term>University hospital erlangen</term><term>University tubingen</term><term>Unselected breast cancer patients</term><term>Variant</term><term>Victorian breast cancer research consortium group leader</term><term>Western australia</term><term>Wiley periodicals</term></keywords><keywords scheme="Wicri" type="geographic" xml:lang="fr"><term>Finlande</term></keywords><keywords scheme="Wicri" type="topic" xml:lang="fr"><term>Cancer</term><term>Consortium</term><term>épidémiologie</term><term>Génétique</term><term>Histologie</term><term>Recherche médicale</term><term>Médecine du travail</term><term>Oulu</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">A recent two‐stage genome‐wide association study (GWAS) identified five novel breast cancer susceptibility loci on chromosomes 9, 10, and 11. To provide more reliable estimates of the relative risk associated with these loci and investigate possible heterogeneity by subtype of breast cancer, we genotyped the variants rs2380205, rs1011970, rs704010, rs614367, and rs10995190 in 39 studies from the Breast Cancer Association Consortium (BCAC), involving 49,608 cases and 48,772 controls of predominantly European ancestry. Four of the variants showed clear evidence of association (P ≤ 3 × 10−9) and weak evidence was observed for rs2380205 (P = 0.06). The strongest evidence was obtained for rs614367, located on 11q13 (per‐allele odds ratio 1.21, P = 4 × 10−39). The association for rs614367 was specific to estrogen receptor (ER)‐positive disease and strongest for ER plus progesterone receptor (PR)‐positive breast cancer, whereas the associations for the other three loci did not differ by tumor subtype. Hum Mutat 33:1123–1132, 2012. © 2012 Wiley Periodicals, Inc.</div></front></TEI><affiliations><list><country><li>Allemagne</li><li>Australie</li><li>Belgique</li><li>Biélorussie</li><li>Canada</li><li>Corée du Sud</li><li>Danemark</li><li>Espagne</li><li>Finlande</li><li>France</li><li>Irlande (pays)</li><li>Italie</li><li>Norvège</li><li>Pays-Bas</li><li>Pologne</li><li>Royaume-Uni</li><li>Russie</li><li>Suède</li><li>Taïwan</li><li>Thaïlande</li><li>États-Unis</li></country><region><li>Angleterre</li><li>Angleterre de l'Est</li><li>Bade-Wurtemberg</li><li>Basse-Saxe</li><li>Bavière</li><li>Californie</li><li>Communauté de Madrid</li><li>District de Cologne</li><li>District de Haute-Bavière</li><li>District de Karlsruhe</li><li>District de Moyenne-Franconie</li><li>District de Stuttgart</li><li>District de Tübingen</li><li>Grand Londres</li><li>Hambourg</li><li>Hollande-Méridionale</li><li>Hollande-Septentrionale</li><li>Hovedstaden</li><li>Lombardie</li><li>Maryland</li><li>Massachusetts</li><li>Minnesota</li><li>Ontario</li><li>Oxfordshire</li><li>Rhénanie-du-Nord-Westphalie</li><li>Région capitale de Séoul</li><li>Sarre (Land)</li><li>Svealand</li><li>Victoria (État)</li><li>Île-de-France</li><li>Østlandet</li></region><settlement><li>Amsterdam</li><li>Bonn</li><li>Cambridge</li><li>Copenhague</li><li>Erlangen</li><li>Hambourg</li><li>Hanovre</li><li>Heidelberg</li><li>Leyde</li><li>Londres</li><li>Madrid</li><li>Melbourne</li><li>Milan</li><li>Munich</li><li>Oslo</li><li>Oxford</li><li>Rotterdam</li><li>Sarrebruck</li><li>Stockholm</li><li>Stuttgart</li><li>Séoul</li><li>Toronto</li><li>Tübingen</li><li>Ulm</li><li>Villejuif</li></settlement><orgName><li>Université Louis-et-Maximilien de Munich</li><li>Université d'Oxford</li><li>Université d'Ulm</li><li>Université de Cambridge</li><li>Université de Melbourne</li><li>Université de Toronto</li></orgName></list><tree><country name="Belgique"><noRegion><name sortKey="Lambrechts, Diether" sort="Lambrechts, Diether" uniqKey="Lambrechts D" first="Diether" last="Lambrechts">Diether Lambrechts</name></noRegion><name sortKey="Neven, Patrick" sort="Neven, Patrick" uniqKey="Neven P" first="Patrick" last="Neven">Patrick Neven</name><name sortKey="Paridaens, Robert" sort="Paridaens, Robert" uniqKey="Paridaens R" first="Robert" last="Paridaens">Robert Paridaens</name><name sortKey="Wildiers, Hans" sort="Wildiers, Hans" uniqKey="Wildiers H" first="Hans" last="Wildiers">Hans Wildiers</name><name sortKey="Yesilyurt, Betul T" sort="Yesilyurt, Betul T" uniqKey="Yesilyurt B" first="Betul T." last="Yesilyurt">Betul T. Yesilyurt</name></country><country name="France"><region name="Île-de-France"><name sortKey="Truong, Therese" sort="Truong, Therese" uniqKey="Truong T" first="Therese" last="Truong">Therese Truong</name></region><name sortKey="Cordina Uverger, Emilie" sort="Cordina Uverger, Emilie" uniqKey="Cordina Uverger E" first="Emilie" last="Cordina-Duverger">Emilie Cordina-Duverger</name><name sortKey="Cordina Uverger, Emilie" sort="Cordina Uverger, Emilie" uniqKey="Cordina Uverger E" first="Emilie" last="Cordina-Duverger">Emilie Cordina-Duverger</name><name sortKey="Guenel, Pascal" sort="Guenel, Pascal" uniqKey="Guenel P" first="Pascal" last="Guénel">Pascal Guénel</name><name sortKey="Guenel, Pascal" sort="Guenel, Pascal" uniqKey="Guenel P" first="Pascal" last="Guénel">Pascal Guénel</name><name sortKey="Menegaux, Florence" sort="Menegaux, Florence" uniqKey="Menegaux F" first="Florence" last="Menegaux">Florence Menegaux</name><name sortKey="Menegaux, Florence" sort="Menegaux, Florence" uniqKey="Menegaux F" first="Florence" last="Menegaux">Florence Menegaux</name><name sortKey="Truong, Therese" sort="Truong, Therese" uniqKey="Truong T" first="Therese" last="Truong">Therese Truong</name></country><country name="Allemagne"><region name="Bade-Wurtemberg"><name sortKey="Justenhoven, Christina" sort="Justenhoven, Christina" uniqKey="Justenhoven C" first="Christina" last="Justenhoven">Christina Justenhoven</name></region><name sortKey="Arndt, Volker" sort="Arndt, Volker" uniqKey="Arndt V" first="Volker" last="Arndt">Volker Arndt</name><name sortKey="Bartram, Claus R" sort="Bartram, Claus R" uniqKey="Bartram C" first="Claus R." last="Bartram">Claus R. Bartram</name><name sortKey="Beckmann, Matthias W" sort="Beckmann, Matthias W" uniqKey="Beckmann M" first="Matthias W." last="Beckmann">Matthias W. Beckmann</name><name sortKey="Bogdanova, Natalia V" sort="Bogdanova, Natalia V" uniqKey="Bogdanova N" first="Natalia V." last="Bogdanova">Natalia V. Bogdanova</name><name sortKey="Bogdanova, Natalia V" sort="Bogdanova, Natalia V" uniqKey="Bogdanova N" first="Natalia V." last="Bogdanova">Natalia V. Bogdanova</name><name sortKey="Brauch, Hiltrud" sort="Brauch, Hiltrud" uniqKey="Brauch H" first="Hiltrud" last="Brauch">Hiltrud Brauch</name><name sortKey="Brauch, Hiltrud" sort="Brauch, Hiltrud" uniqKey="Brauch H" first="Hiltrud" last="Brauch">Hiltrud Brauch</name><name sortKey="Brauch, Hiltrud" sort="Brauch, Hiltrud" uniqKey="Brauch H" first="Hiltrud" last="Brauch">Hiltrud Brauch</name><name sortKey="Bremer, Michael" sort="Bremer, Michael" uniqKey="Bremer M" first="Michael" last="Bremer">Michael Bremer</name><name sortKey="Brenner, Hermann" sort="Brenner, Hermann" uniqKey="Brenner H" first="Hermann" last="Brenner">Hermann Brenner</name><name sortKey="Bruning, Thomas" sort="Bruning, Thomas" uniqKey="Bruning T" first="Thomas" last="Brüning">Thomas Brüning</name><name sortKey="Burwinkel, Barbara" sort="Burwinkel, Barbara" uniqKey="Burwinkel B" first="Barbara" last="Burwinkel">Barbara Burwinkel</name><name sortKey="Burwinkel, Barbara" sort="Burwinkel, Barbara" uniqKey="Burwinkel B" first="Barbara" last="Burwinkel">Barbara Burwinkel</name><name sortKey="Chang Laude, Jenny" sort="Chang Laude, Jenny" uniqKey="Chang Laude J" first="Jenny" last="Chang-Claude">Jenny Chang-Claude</name><name sortKey="Dork, Thilo" sort="Dork, Thilo" uniqKey="Dork T" first="Thilo" last="Dörk">Thilo Dörk</name><name sortKey="Eilber, Ursel" sort="Eilber, Ursel" uniqKey="Eilber U" first="Ursel" last="Eilber">Ursel Eilber</name><name sortKey="Ekici, Arif B" sort="Ekici, Arif B" uniqKey="Ekici A" first="Arif B." last="Ekici">Arif B. Ekici</name><name sortKey="Flesch Anys, Dieter" sort="Flesch Anys, Dieter" uniqKey="Flesch Anys D" first="Dieter" last="Flesch-Janys">Dieter Flesch-Janys</name><name sortKey="Hamann, Ute" sort="Hamann, Ute" uniqKey="Hamann U" first="Ute" last="Hamann">Ute Hamann</name><name sortKey="Hein, Rebecca" sort="Hein, Rebecca" uniqKey="Hein R" first="Rebecca" last="Hein">Rebecca Hein</name><name sortKey="Hillemanns, Peter" sort="Hillemanns, Peter" uniqKey="Hillemanns P" first="Peter" last="Hillemanns">Peter Hillemanns</name><name sortKey="Karstens, Johann H" sort="Karstens, Johann H" uniqKey="Karstens J" first="Johann H." last="Karstens">Johann H. Karstens</name><name sortKey="Ko, Yon Schun" sort="Ko, Yon Schun" uniqKey="Ko Y" first="Yon-Dschun" last="Ko">Yon-Dschun Ko</name><name sortKey="Marme, Federik" sort="Marme, Federik" uniqKey="Marme F" first="Federik" last="Marmé">Federik Marmé</name><name sortKey="Marme, Federik" sort="Marme, Federik" uniqKey="Marme F" first="Federik" last="Marmé">Federik Marmé</name><name sortKey="Meindl, Alfons" sort="Meindl, Alfons" uniqKey="Meindl A" first="Alfons" last="Meindl">Alfons Meindl</name><name sortKey="Muller, Heiko" sort="Muller, Heiko" uniqKey="Muller H" first="Heiko" last="Müller">Heiko Müller</name><name sortKey="Nickels, Stefan" sort="Nickels, Stefan" uniqKey="Nickels S" first="Stefan" last="Nickels">Stefan Nickels</name><name sortKey="Schmutzler, Rita K" sort="Schmutzler, Rita K" uniqKey="Schmutzler R" first="Rita K." last="Schmutzler">Rita K. Schmutzler</name><name sortKey="Schneeweiss, Andreas" sort="Schneeweiss, Andreas" uniqKey="Schneeweiss A" first="Andreas" last="Schneeweiss">Andreas Schneeweiss</name><name sortKey="Schneeweiss, Andreas" sort="Schneeweiss, Andreas" uniqKey="Schneeweiss A" first="Andreas" last="Schneeweiss">Andreas Schneeweiss</name><name sortKey="Schott, Sarah" sort="Schott, Sarah" uniqKey="Schott S" first="Sarah" last="Schott">Sarah Schott</name><name sortKey="Schulz Endtland, Ruediger" sort="Schulz Endtland, Ruediger" uniqKey="Schulz Endtland R" first="Ruediger" last="Schulz-Wendtland">Ruediger Schulz-Wendtland</name><name sortKey="Schurmann, Peter" sort="Schurmann, Peter" uniqKey="Schurmann P" first="Peter" last="Schürmann">Peter Schürmann</name><name sortKey="Sohn, Christof" sort="Sohn, Christof" uniqKey="Sohn C" first="Christof" last="Sohn">Christof Sohn</name><name sortKey="Stegmaier, Christa" sort="Stegmaier, Christa" uniqKey="Stegmaier C" first="Christa" last="Stegmaier">Christa Stegmaier</name><name sortKey="Wang Ohrke, Shan" sort="Wang Ohrke, Shan" uniqKey="Wang Ohrke S" first="Shan" last="Wang-Gohrke">Shan Wang-Gohrke</name></country><country name="Royaume-Uni"><region name="Angleterre"><name sortKey="Humphreys, Manjeet K" sort="Humphreys, Manjeet K" uniqKey="Humphreys M" first="Manjeet K." last="Humphreys">Manjeet K. 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